Detailed information of TA system TA081248

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ParST/RES-Xre
• Location: 5073632..5074419
• Replicon: chromosome
• Accession: NZ_CP023422
• Organism: Janthinobacterium svalbardensis strain PAMC 27463

Toxin (Protein)

• Gene name: ParT
• Uniprot ID: -
• Locus tag: CNX70_RS22585
• Protein ID: WP_096237263.1
• Coordinates: 5073632..5074102 (-)
• Length: 157 a.a.

Antitoxin (Protein)

• Gene name: ParS
• Uniprot ID: -
• Locus tag: CNX70_RS22590
• Protein ID: WP_096238630.1
• Coordinates: 5074099..5074419 (-)
• Length: 107 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CNX70_RS22560	5069825..5070082	-	258	Protein_4467	FABP family protein	-
CNX70_RS22565	5070167..5070565	-	399	WP_096237255.1	hypothetical protein	-
CNX70_RS22570	5070567..5071370	-	804	WP_096237257.1	type I methionyl aminopeptidase	-
CNX70_RS22575	5071388..5071987	-	600	WP_096237259.1	TetR/AcrR family transcriptional regulator	-
CNX70_RS22580	5072110..5073624	+	1515	WP_096237261.1	AMP nucleosidase	-
CNX70_RS22585	5073632..5074102	-	471	WP_096237263.1	RES family NAD+ phosphorylase	Toxin
CNX70_RS22590	5074099..5074419	-	321	WP_096238630.1	MbcA/ParS/Xre antitoxin family protein	Antitoxin
CNX70_RS22595	5074709..5075179	-	471	WP_096237265.1	DUF1854 domain-containing protein	-
CNX70_RS22600	5075182..5077296	-	2115	WP_208624582.1	ATP-binding cassette domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (4-150)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (3-36)

Sequences

Toxin

Protein

• Length: 157 a.a.
• Molecular weight: 16791.25 Da
• Isoelectric Point: 9.4424

>T81248 WP_096237263.1 NZ_CP023422:c5074102-5073632 [Janthinobacterium svalbardensis]
MNVLWRIAVETPAYPASDLSGTGARITGGRWNSKGAPVVYCSTSIALATLETVHYLRGGGLPFNRYLVRIAIPDGVWNAR
QVLDPFPGCWDAIPAGLSGKRAGDGWIAAGKSALLLVPSVIVPDEYNVLLNPRHADAAAVTASTVRRWSYDPRFFP

Nucleotide

• Length: 471 bp

>T81248 NZ_CP023422:c5074102-5073632 [Janthinobacterium svalbardensis]
ATGAACGTGCTCTGGCGTATTGCCGTCGAGACGCCAGCCTATCCCGCCAGTGACCTGAGCGGCACCGGCGCGAGGATCAC
GGGCGGCCGCTGGAACAGCAAGGGCGCGCCCGTCGTGTATTGCTCGACGAGTATCGCCCTGGCCACCCTGGAAACCGTCC
ATTACCTGCGGGGCGGCGGCCTGCCGTTCAACCGTTACCTGGTGCGTATCGCCATTCCCGATGGCGTATGGAACGCGCGC
CAGGTACTCGACCCATTTCCCGGCTGCTGGGACGCCATACCGGCCGGCTTGTCGGGCAAGCGGGCCGGCGATGGCTGGAT
TGCAGCGGGAAAATCTGCCTTGCTGCTGGTGCCTTCCGTGATCGTGCCCGACGAATACAATGTCTTGCTCAACCCCCGCC
ATGCCGATGCAGCAGCGGTCACCGCCAGCACCGTCCGGCGGTGGAGCTACGATCCCCGCTTTTTCCCTTGA

Antitoxin

Protein

• Length: 107 a.a.
• Molecular weight: 11342.93 Da
• Isoelectric Point: 4.4367

>AT81248 WP_096238630.1 NZ_CP023422:c5074419-5074099 [Janthinobacterium svalbardensis]
MSKEFLLSSLGLSRATISRKEKDASLLSKDESERVLGVETLIGMVQAMVEQSGDPAGFDAARWVSDWLSKPLPALAGATP
ASYMDTFEGQKLVAELLSMTQSGAYA

Nucleotide

• Length: 321 bp

>AT81248 NZ_CP023422:c5074419-5074099 [Janthinobacterium svalbardensis]
ATGAGCAAGGAATTCCTGTTGTCCAGCCTGGGGTTGTCGCGCGCCACCATCAGCCGCAAGGAGAAAGACGCCAGCTTGCT
GTCGAAGGATGAATCGGAGCGCGTACTGGGTGTTGAAACCCTGATCGGCATGGTGCAGGCGATGGTCGAACAATCGGGCG
ATCCCGCCGGCTTTGACGCGGCGCGCTGGGTCTCCGATTGGCTGAGCAAGCCGCTGCCTGCGCTGGCGGGAGCGACGCCG
GCCAGCTACATGGATACCTTCGAGGGGCAAAAACTGGTGGCGGAATTGCTGTCCATGACGCAGAGCGGAGCCTATGCATG
A