Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Fic(toxin)
Location 2965652..2966217 Replicon chromosome
Accession NZ_CP023407
Organism Streptomyces fungicidicus strain TXX3120

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag CNQ36_RS13380 Protein ID WP_121546168.1
Coordinates 2965652..2966020 (-) Length 123 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag CNQ36_RS13385 Protein ID WP_121546169.1
Coordinates 2966020..2966217 (-) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CNQ36_RS13360 2960728..2961705 + 978 WP_121546166.1 glycine betaine ABC transporter substrate-binding protein -
CNQ36_RS13365 2961702..2962493 - 792 WP_121546167.1 hypothetical protein -
CNQ36_RS13370 2962802..2963443 - 642 WP_040907076.1 helix-turn-helix domain-containing protein -
CNQ36_RS13375 2963728..2965527 - 1800 WP_004930870.1 DEAD/DEAH box helicase -
CNQ36_RS13380 2965652..2966020 - 369 WP_121546168.1 Fic family protein Toxin
CNQ36_RS13385 2966020..2966217 - 198 WP_121546169.1 hypothetical protein Antitoxin
CNQ36_RS13390 2966250..2967710 - 1461 WP_121546170.1 MFS transporter -
CNQ36_RS13395 2968016..2969275 + 1260 WP_163013258.1 hypothetical protein -
CNQ36_RS13400 2969292..2970470 - 1179 WP_121546172.1 SUKH-4 family immunity protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(4-80)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13745.67 Da        Isoelectric Point: 4.6413

>T81203 WP_121546168.1 NZ_CP023407:c2966020-2965652 [Streptomyces fungicidicus]
MYYLTLPELLNLAKRLGEDVVRDYGLLDSALARPQSSVFGQDAYPDVWQKAAALMESLARNHALVDGNKRLAWYATWVFL
HMNGHPLDPDFDVDEAEQFVLDVCQGALDVPKIAAQLPRFAR

Download         Length: 369 bp

>T81203 NZ_CP023407:c2966020-2965652 [Streptomyces fungicidicus]
ATGTACTACCTCACCTTGCCCGAGTTGCTGAACCTCGCGAAGCGGCTCGGGGAGGACGTGGTGCGCGACTACGGGCTGCT
CGACTCGGCCTTGGCGCGTCCGCAGTCGAGCGTGTTCGGCCAGGACGCCTACCCGGACGTGTGGCAGAAGGCCGCGGCAC
TGATGGAGTCCCTCGCTCGCAACCATGCCCTCGTCGACGGGAACAAGCGCCTCGCCTGGTACGCGACCTGGGTCTTCCTG
CATATGAACGGGCATCCGCTCGACCCGGACTTCGACGTGGACGAGGCGGAGCAGTTCGTGCTGGACGTCTGCCAGGGCGC
ACTGGACGTCCCCAAGATCGCAGCTCAGTTGCCCCGCTTCGCGCGCTGA

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7349.21 Da        Isoelectric Point: 5.5900

>AT81203 WP_121546169.1 NZ_CP023407:c2966217-2966020 [Streptomyces fungicidicus]
MAGLNLRFTDEELDALRERAAAEGRSMQTFAHDAVIKAINEHSRLFNEAADHVLRASEELNRRLA

Download         Length: 198 bp

>AT81203 NZ_CP023407:c2966217-2966020 [Streptomyces fungicidicus]
ATGGCTGGACTGAACCTGCGGTTTACTGACGAAGAGCTCGATGCCCTGCGTGAGCGTGCGGCTGCGGAAGGGCGCAGCAT
GCAGACCTTCGCGCACGACGCGGTGATCAAGGCCATAAACGAACACTCGAGGCTGTTCAACGAGGCGGCCGACCACGTGC
TGAGGGCCAGCGAAGAGCTGAACCGGAGGCTCGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References