Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2016436..2016707 Replicon chromosome
Accession NZ_CP023377
Organism Escherichia coli strain 127

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2016566..2016669 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2016436..2016707 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CNQ50_RS10485 2012991..2013653 - 663 WP_000944256.1 exodeoxyribonuclease X -
CNQ50_RS10490 2013677..2014333 - 657 WP_000011660.1 carbon-nitrogen hydrolase family protein -
CNQ50_RS10495 2014435..2014665 - 231 WP_000916763.1 DNA polymerase III subunit theta -
CNQ50_RS10500 2014804..2015178 + 375 WP_000255065.1 CopC domain-containing protein YobA -
CNQ50_RS10505 2015182..2016054 + 873 WP_000879298.1 copper homeostasis membrane protein CopD -
CNQ50_RS10510 2016067..2016408 + 342 WP_000976472.1 YebY family protein -
- 2016436..2016707 - 272 - - Antitoxin
- 2016566..2016669 + 104 - - Toxin
CNQ50_RS10515 2016804..2017460 + 657 WP_000812733.1 protein-serine/threonine phosphatase -
CNQ50_RS10520 2017461..2017652 - 192 WP_001338167.1 YebW family protein -
CNQ50_RS10525 2017757..2017993 - 237 WP_001338166.1 DUF1480 family protein -
CNQ50_RS10530 2018111..2019550 - 1440 WP_001338165.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T81035 NZ_CP023377:2016566-2016669 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT81035 NZ_CP023377:c2016707-2016436 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References