Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2241269..2241540 Replicon chromosome
Accession NZ_CP023364
Organism Escherichia coli strain 144

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2241399..2241502 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2241269..2241540 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CNQ53_RS12120 2237824..2238486 - 663 WP_000944256.1 exodeoxyribonuclease X -
CNQ53_RS12125 2238510..2239166 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein -
CNQ53_RS12130 2239268..2239498 - 231 WP_000916763.1 DNA polymerase III subunit theta -
CNQ53_RS12135 2239637..2240011 + 375 WP_000168747.1 CopC domain-containing protein YobA -
CNQ53_RS12140 2240015..2240887 + 873 WP_001551232.1 copper homeostasis membrane protein CopD -
CNQ53_RS12145 2240900..2241241 + 342 WP_000976472.1 YebY family protein -
- 2241269..2241540 - 272 - - Antitoxin
- 2241399..2241502 + 104 - - Toxin
CNQ53_RS12150 2241637..2242293 + 657 WP_001551231.1 protein-serine/threonine phosphatase -
CNQ53_RS12155 2242294..2242485 - 192 WP_001296140.1 YebW family protein -
CNQ53_RS12160 2242590..2242826 - 237 WP_001295499.1 DUF1480 family protein -
CNQ53_RS12165 2242944..2244383 - 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2233959..2249770 15811


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T80931 NZ_CP023364:2241399-2241502 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT80931 NZ_CP023364:c2241540-2241269 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References