Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2246486..2246757 Replicon chromosome
Accession NZ_CP023353
Organism Escherichia coli strain 746

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2246616..2246719 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2246486..2246757 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CNQ56_RS11320 2243041..2243703 - 663 WP_000944256.1 exodeoxyribonuclease X -
CNQ56_RS11325 2243727..2244383 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein -
CNQ56_RS11330 2244485..2244715 - 231 WP_000916763.1 DNA polymerase III subunit theta -
CNQ56_RS11335 2244854..2245228 + 375 WP_000168747.1 CopC domain-containing protein YobA -
CNQ56_RS11340 2245232..2246104 + 873 WP_001551232.1 copper homeostasis membrane protein CopD -
CNQ56_RS11345 2246117..2246458 + 342 WP_000976472.1 YebY family protein -
- 2246486..2246757 - 272 - - Antitoxin
- 2246616..2246719 + 104 - - Toxin
CNQ56_RS11350 2246854..2247510 + 657 WP_001551231.1 protein-serine/threonine phosphatase -
CNQ56_RS11355 2247511..2247702 - 192 WP_001296140.1 YebW family protein -
CNQ56_RS11360 2247807..2248043 - 237 WP_001295499.1 DUF1480 family protein -
CNQ56_RS11365 2248161..2249600 - 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2221990..2262597 40607


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T80831 NZ_CP023353:2246616-2246719 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT80831 NZ_CP023353:c2246757-2246486 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References