Detailed information of TA system TA080741

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/-
• Location: 3476168..3476613
• Replicon: chromosome
• Accession: NZ_CP023315
• Organism: Caulobacter vibrioides strain CB13b1a

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CA606_RS16360
• Protein ID: WP_096053573.1
• Coordinates: 3476338..3476613 (+)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: CA606_RS16355
• Protein ID: WP_096053574.1
• Coordinates: 3476168..3476350 (+)
• Length: 61 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CA606_RS16345	3473339..3474619	-	1281	WP_096053576.1	FAD-binding oxidoreductase	-
CA606_RS16350	3474695..3476092	-	1398	WP_096053575.1	glutamine synthetase family protein	-
CA606_RS16355	3476168..3476350	+	183	WP_096053574.1	antitoxin	Antitoxin
CA606_RS16360	3476338..3476613	+	276	WP_096053573.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CA606_RS16365	3476616..3478019	-	1404	WP_096053572.1	aspartate aminotransferase family protein	-
CA606_RS16370	3478016..3478780	-	765	WP_096053571.1	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	-
CA606_RS16375	3478941..3480080	-	1140	WP_096053570.1	ABC transporter ATP-binding protein	-
CA606_RS16380	3480262..3481119	-	858	WP_096053569.1	ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-89)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 9952.53 Da
• Isoelectric Point: 12.0654

>T80741 WP_096053573.1 NZ_CP023315:3476338-3476613 [Caulobacter vibrioides]
VAQVVWTDRAMADIDAIVAYITSQSRPIAAQRLGQRLLAAGASLADHPERGRLSTRGRRELVAVPPYALRYRIVGDRVVI
GGVRHGARRPL

Nucleotide

• Length: 276 bp

>T80741 NZ_CP023315:3476338-3476613 [Caulobacter vibrioides]
GTGGCGCAAGTAGTCTGGACTGACCGTGCGATGGCCGATATCGACGCCATCGTCGCCTACATTACCAGTCAATCGCGCCC
GATCGCAGCACAACGATTGGGCCAAAGATTGCTCGCAGCCGGCGCGAGCTTGGCGGACCATCCAGAACGCGGTCGGCTCA
GCACGCGAGGACGTCGCGAACTGGTGGCCGTCCCGCCCTATGCGCTGCGATACCGCATTGTCGGCGACCGTGTCGTCATT
GGCGGTGTACGCCATGGGGCGCGTCGACCTCTCTAG

Antitoxin

Protein

• Length: 61 a.a.
• Molecular weight: 6790.45 Da
• Isoelectric Point: 4.0676

>AT80741 WP_096053574.1 NZ_CP023315:3476168-3476350 [Caulobacter vibrioides]
MAEPDPDIFDEFEDEADRLADAEADADLAAGRVVPHERVVDWLKSLGTPHQLPTPYSWRK

Nucleotide

• Length: 183 bp

>AT80741 NZ_CP023315:3476168-3476350 [Caulobacter vibrioides]
ATGGCCGAGCCTGACCCCGACATCTTCGACGAGTTTGAAGACGAAGCTGACCGCTTGGCCGATGCCGAGGCCGACGCCGA
CTTGGCGGCTGGTCGTGTTGTGCCCCACGAACGCGTCGTGGATTGGCTGAAGTCGCTCGGAACGCCACACCAGCTTCCGA
CTCCGTACTCGTGGCGCAAGTAG