Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 3235679..3236322 Replicon chromosome
Accession NZ_CP023315
Organism Caulobacter vibrioides strain CB13b1a

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag CA606_RS15335 Protein ID WP_096053748.1
Coordinates 3236032..3236322 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag CA606_RS15330 Protein ID WP_096053984.1
Coordinates 3235679..3236005 (-) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CA606_RS15310 3230958..3231890 - 933 WP_096053751.1 DMT family transporter -
CA606_RS15315 3232097..3233473 - 1377 WP_096053750.1 peptidoglycan DD-metalloendopeptidase family protein -
CA606_RS15320 3233732..3234427 - 696 WP_010920871.1 cell cycle two-component system response regulator CtrA -
CA606_RS15325 3234842..3235636 - 795 WP_096053749.1 LytTR family DNA-binding domain-containing protein -
CA606_RS15330 3235679..3236005 - 327 WP_096053984.1 type II toxin-antitoxin system antitoxin HigA Antitoxin
CA606_RS15335 3236032..3236322 - 291 WP_096053748.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CA606_RS15340 3236527..3237534 + 1008 WP_096053747.1 dienelactone hydrolase -
CA606_RS15345 3237593..3238927 + 1335 WP_096053746.1 flagellar protein export ATPase FliI -
CA606_RS15350 3238930..3239349 + 420 WP_096053745.1 flagella biosynthesis chaperone FliJ -
CA606_RS15355 3239358..3239556 + 199 Protein_3021 hypothetical protein -
CA606_RS15360 3239483..3240550 + 1068 WP_096053744.1 endo-1,4-beta-xylanase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-95)

Antitoxin

Uncharacterized protein HI1420

(6-89)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10661.48 Da        Isoelectric Point: 11.6097

>T80740 WP_096053748.1 NZ_CP023315:c3236322-3236032 [Caulobacter vibrioides]
MIEIVETVAFRAWRAGLRDAKGRRAISTRLARLAQGLFGDFRTVGEGVGELRIHVGPGYRLYFVRRGDVLIILLHGGDKG
AQARDIEKAKMIARSL

Download         Length: 291 bp

>T80740 NZ_CP023315:c3236322-3236032 [Caulobacter vibrioides]
ATGATCGAGATCGTAGAAACCGTTGCGTTCAGGGCTTGGCGCGCCGGCTTGCGAGACGCGAAAGGGCGGCGGGCGATTTC
CACCCGGCTGGCGCGTCTGGCTCAGGGGCTGTTTGGAGATTTTCGGACAGTCGGCGAGGGCGTTGGCGAACTGAGAATCC
ATGTCGGACCGGGCTATCGGCTCTATTTTGTCCGACGCGGCGATGTGTTGATCATTCTCCTGCACGGCGGCGACAAGGGG
GCCCAGGCAAGGGACATCGAAAAAGCCAAGATGATCGCGAGAAGTCTTTGA

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 11524.99 Da        Isoelectric Point: 4.0901

>AT80740 WP_096053984.1 NZ_CP023315:c3236005-3235679 [Caulobacter vibrioides]
MVELVRFDPVEEIDDAEAVAVFLADAFDTGDADYIQHMLGLIARSKGMAEVAEKAGLGRESLYKALKDGASPRFDTILRV
VHALGLKLALVSATEANFAEDADDEAAA

Download         Length: 327 bp

>AT80740 NZ_CP023315:c3236005-3235679 [Caulobacter vibrioides]
ATGGTTGAACTGGTTCGCTTTGACCCTGTCGAAGAGATCGACGACGCCGAGGCGGTCGCCGTGTTTCTGGCCGACGCCTT
CGATACGGGCGACGCCGACTATATCCAGCACATGCTGGGGCTGATCGCTCGCTCCAAGGGGATGGCCGAGGTCGCCGAGA
AAGCCGGCTTGGGGCGCGAGAGCCTCTACAAGGCGCTGAAAGACGGCGCTTCGCCGCGTTTCGACACGATCTTGCGTGTG
GTCCATGCCTTGGGGCTGAAGTTGGCCCTGGTCAGCGCGACCGAGGCCAATTTCGCCGAAGACGCGGACGACGAAGCCGC
CGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References