Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) shpA-brnA/BrnT_toxin-BrnA
Location 3216945..3217464 Replicon chromosome
Accession NZ_CP023315
Organism Caulobacter vibrioides strain CB13b1a

Toxin (Protein)


Gene name shpA Uniprot ID -
Locus tag CA606_RS15235 Protein ID WP_096050348.1
Coordinates 3216945..3217220 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag CA606_RS15240 Protein ID WP_096050347.1
Coordinates 3217213..3217464 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CA606_RS15220 3213535..3213903 - 369 WP_096050351.1 response regulator -
CA606_RS15225 3213907..3215499 - 1593 WP_096050350.1 PAS domain-containing protein -
CA606_RS15230 3215593..3216879 - 1287 WP_096050349.1 HlyC/CorC family transporter -
CA606_RS15235 3216945..3217220 + 276 WP_096050348.1 BrnT family toxin Toxin
CA606_RS15240 3217213..3217464 + 252 WP_096050347.1 BrnA antitoxin family protein Antitoxin
CA606_RS15245 3217559..3217999 + 441 WP_096050346.1 hypothetical protein -
CA606_RS15250 3217968..3218687 - 720 WP_181242620.1 phosphatase PAP2 family protein -
CA606_RS15255 3218765..3218941 + 177 WP_096050344.1 hypothetical protein -
CA606_RS15260 3218974..3219984 + 1011 WP_096050343.1 cobaltochelatase subunit CobS -
CA606_RS15265 3220126..3221286 - 1161 WP_096053754.1 serine hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(7-81)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(5-78)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10423.80 Da        Isoelectric Point: 8.0800

>T80739 WP_096050348.1 NZ_CP023315:3216945-3217220 [Caulobacter vibrioides]
IQFDVQFDPAKNQANIAKHGVSLERAPEMDIRAVLVDERHDYGEVRYRALGFIDGVAHCLVFTDRQGELRAISLRRAHQK
EMKRYVSQANG

Download         Length: 276 bp

>T80739 NZ_CP023315:3216945-3217220 [Caulobacter vibrioides]
ATACAATTTGATGTGCAGTTCGACCCGGCCAAGAACCAGGCGAATATCGCCAAGCATGGCGTATCGCTCGAACGAGCCCC
AGAAATGGATATTCGGGCCGTTCTGGTGGACGAGCGGCATGACTATGGCGAGGTGCGCTATCGGGCTCTCGGGTTCATTG
ATGGCGTCGCTCACTGCCTGGTTTTCACCGACCGCCAAGGCGAGTTGCGAGCCATCAGCTTGCGTCGCGCCCACCAGAAG
GAGATGAAGCGCTATGTCTCGCAAGCCAATGGCTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9069.34 Da        Isoelectric Point: 10.6606

>AT80739 WP_096050347.1 NZ_CP023315:3217213-3217464 [Caulobacter vibrioides]
MADPENPEWTAGDVARSKGPESLPAHVLAAFPKTAARVRGPQKSETKVPVSIRLDRSVVDYFKAQGPGWQSRINEALAGM
IRR

Download         Length: 252 bp

>AT80739 NZ_CP023315:3217213-3217464 [Caulobacter vibrioides]
ATGGCTGACCCGGAAAATCCGGAATGGACTGCGGGTGACGTCGCGCGATCCAAGGGGCCGGAGTCCTTGCCGGCTCATGT
CCTGGCGGCCTTTCCAAAAACCGCCGCTCGGGTGCGTGGCCCTCAGAAGTCCGAGACCAAGGTGCCGGTGTCCATCCGCC
TGGACCGCTCGGTGGTCGACTACTTCAAGGCCCAGGGGCCAGGTTGGCAGAGCCGGATCAATGAGGCGCTCGCGGGAATG
ATCCGCCGATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References