Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 1021141..1021979 Replicon chromosome
Accession NZ_CP023315
Organism Caulobacter vibrioides strain CB13b1a

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag CA606_RS04795 Protein ID WP_096053868.1
Coordinates 1021141..1021563 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag CA606_RS04800 Protein ID WP_096052160.1
Coordinates 1021656..1021979 (-) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CA606_RS04780 1017222..1018772 + 1551 WP_096052163.1 tryptophan 7-halogenase -
CA606_RS04785 1018875..1020125 - 1251 WP_096052162.1 three-Cys-motif partner protein TcmP -
CA606_RS04790 1020153..1020929 - 777 WP_096052161.1 DUF5131 family protein -
CA606_RS04795 1021141..1021563 - 423 WP_096053868.1 GNAT family N-acetyltransferase Toxin
CA606_RS04800 1021656..1021979 - 324 WP_096052160.1 DUF1778 domain-containing protein Antitoxin
CA606_RS04805 1022129..1022731 - 603 WP_096052159.1 peptidylprolyl isomerase -
CA606_RS04810 1022931..1024583 + 1653 WP_096052158.1 MFS transporter -
CA606_RS04815 1024670..1025263 + 594 WP_181242789.1 RNA polymerase sigma factor -
CA606_RS04820 1025227..1026222 + 996 WP_096052156.1 FecR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(15-115)

Antitoxin

Vibrio phage ICP1, Orf50

(21-106)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15129.30 Da        Isoelectric Point: 8.6813

>T80735 WP_096053868.1 NZ_CP023315:c1021563-1021141 [Caulobacter vibrioides]
MNDWLKQRAAKNESRFSRTYVVCEGDQVVGYYCIAAGAVERAAAPGKVRRNAPNAIPVSIIGRLAVSRTHAGQGLGADLL
ADALRRIAVASQSIGIGAVLVQAKDDAAKRFYLRCAEFEEYPEESRTLYLPIETVVAAFG

Download         Length: 423 bp

>T80735 NZ_CP023315:c1021563-1021141 [Caulobacter vibrioides]
CTGAACGACTGGCTCAAGCAGCGGGCGGCCAAGAACGAGAGCCGCTTCTCTCGCACCTATGTCGTTTGCGAGGGCGACCA
GGTCGTCGGCTACTACTGCATCGCCGCCGGCGCCGTGGAACGGGCCGCAGCCCCCGGCAAGGTCCGCCGCAATGCGCCCA
ACGCCATCCCGGTCTCGATCATCGGCCGCCTGGCCGTCAGCCGCACCCACGCCGGCCAAGGCCTGGGCGCGGACCTCCTG
GCCGACGCCCTGAGGCGGATCGCCGTGGCCTCCCAGAGCATCGGCATCGGCGCGGTGCTGGTCCAGGCCAAGGACGACGC
CGCCAAGCGCTTCTACCTGCGCTGCGCCGAGTTCGAGGAGTATCCGGAGGAGAGCCGGACGCTGTATCTGCCGATTGAAA
CGGTGGTGGCGGCGTTTGGGTAG

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11618.37 Da        Isoelectric Point: 10.3438

>AT80735 WP_096052160.1 NZ_CP023315:c1021979-1021656 [Caulobacter vibrioides]
MAKTLTKAAPTAPAHGEPASGAKGSINLRIEAQTRQLIDDAAAVLGKTRTEFMIDSARAQAIDVLLDQRLFVLDAERYDA
FMHALDNPPAPGPKLRALLRRTPAWSR

Download         Length: 324 bp

>AT80735 NZ_CP023315:c1021979-1021656 [Caulobacter vibrioides]
ATGGCGAAAACCCTGACCAAGGCCGCCCCGACCGCGCCGGCGCACGGTGAACCAGCGTCTGGCGCCAAGGGTTCGATCAA
TCTGCGGATCGAGGCCCAGACCCGGCAGTTGATCGACGACGCCGCTGCGGTGCTGGGCAAGACCCGCACCGAGTTCATGA
TCGACAGCGCGCGCGCCCAGGCGATCGATGTCCTGCTGGACCAGCGCCTCTTCGTGCTCGACGCCGAGCGCTACGACGCG
TTCATGCACGCGCTCGACAACCCGCCGGCCCCAGGCCCCAAGCTGCGCGCCCTGTTGCGGCGCACACCCGCGTGGTCGCG
CTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References