Detailed information of TA system TA080733

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/-
• Location: 808731..809272
• Replicon: chromosome
• Accession: NZ_CP023315
• Organism: Caulobacter vibrioides strain CB13b1a

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CA606_RS03850
• Protein ID: WP_096052313.1
• Coordinates: 808731..809012 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: CA606_RS03855
• Protein ID: WP_096052312.1
• Coordinates: 809009..809272 (-)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CA606_RS03840	805625..807241	-	1617	WP_096052315.1	carboxylesterase/lipase family protein	-
CA606_RS03845	807327..808655	-	1329	WP_096052314.1	cellulase family glycosylhydrolase	-
CA606_RS03850	808731..809012	-	282	WP_096052313.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CA606_RS03855	809009..809272	-	264	WP_096052312.1	type II toxin-antitoxin system antitoxin RelB1	Antitoxin
CA606_RS03860	809311..812400	-	3090	WP_096052311.1	bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase PutA	-
CA606_RS03865	812842..813309	+	468	WP_096052310.1	Lrp/AsnC ligand binding domain-containing protein	-
CA606_RS03870	813410..813577	-	168	WP_181242775.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-92)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10580.24 Da
• Isoelectric Point: 11.1493

>T80733 WP_096052313.1 NZ_CP023315:c809012-808731 [Caulobacter vibrioides]
VTFTVLVSVRAKRDFNRLIVWLFERDPRAAARLGPLLEDAIDSLTEAPSRGRPVGPTVREISIPFGQSAYVIRYRLLGSS
VYVTRIWHGLEQR

Nucleotide

• Length: 282 bp

>T80733 NZ_CP023315:c809012-808731 [Caulobacter vibrioides]
GTGACCTTCACGGTCTTGGTGTCCGTCAGGGCCAAGAGAGACTTCAACCGTCTCATCGTCTGGCTTTTCGAGCGTGACCC
CCGAGCAGCGGCTAGACTGGGCCCCCTTCTGGAAGACGCCATCGACAGTTTGACCGAGGCGCCGTCGCGAGGTCGCCCGG
TTGGTCCTACCGTCCGCGAGATCAGCATTCCATTTGGTCAGAGCGCCTATGTGATCCGCTACCGGCTCCTCGGCTCCAGC
GTGTATGTCACCCGGATCTGGCACGGCCTTGAGCAACGATAG

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 9202.32 Da
• Isoelectric Point: 4.2560

>AT80733 WP_096052312.1 NZ_CP023315:c809272-809009 [Caulobacter vibrioides]
MADGFDIHIDQEQAARLKVVADRLGMTASEYAVALIDAGLTGAAPKAIDPDPAIDEAIADAIERGDEPAISRDEFRAHMR
RVTAGLG

Nucleotide

• Length: 264 bp

>AT80733 NZ_CP023315:c809272-809009 [Caulobacter vibrioides]
ATGGCCGATGGCTTCGACATTCATATCGATCAAGAGCAGGCCGCCCGGCTGAAGGTCGTTGCCGACCGCCTGGGCATGAC
CGCGTCCGAGTACGCCGTTGCGCTGATCGACGCAGGCCTGACAGGCGCGGCGCCTAAAGCGATCGATCCGGACCCCGCCA
TCGACGAGGCCATCGCCGACGCCATCGAGCGGGGCGACGAGCCGGCGATTTCACGCGATGAGTTCCGCGCTCATATGCGT
CGCGTGACTGCGGGCCTGGGGTGA