Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 3701504..3702177 Replicon chromosome
Accession NZ_CP023313
Organism Caulobacter vibrioides strain CB2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CA608_RS18105 Protein ID WP_096034424.1
Coordinates 3701785..3702177 (+) Length 131 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CA608_RS18100 Protein ID WP_096034423.1
Coordinates 3701504..3701788 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CA608_RS18070 3697137..3697934 - 798 WP_010921213.1 3-hydroxybutyrate dehydrogenase -
CA608_RS18075 3698032..3698799 - 768 WP_010921214.1 peroxide stress protein YaaA -
CA608_RS18080 3698935..3699387 + 453 WP_096034421.1 hypothetical protein -
CA608_RS18085 3699384..3699680 + 297 WP_010921216.1 transcriptional regulator -
CA608_RS18090 3699724..3700032 + 309 WP_010921217.1 hypothetical protein -
CA608_RS18095 3700029..3701438 - 1410 WP_096034422.1 FAD-binding oxidoreductase -
CA608_RS18100 3701504..3701788 + 285 WP_096034423.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
CA608_RS18105 3701785..3702177 + 393 WP_096034424.1 type II toxin-antitoxin system VapC family toxin Toxin
CA608_RS18110 3702174..3703151 - 978 WP_096034425.1 threonylcarbamoyl-AMP synthase -
CA608_RS18115 3703082..3704365 - 1284 WP_096034426.1 YceI family protein -
CA608_RS18120 3704399..3705040 - 642 WP_010921221.1 YceI family protein -
CA608_RS18125 3705183..3706994 + 1812 WP_096034427.1 acyl-CoA dehydrogenase C-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-125)

Antitoxin

Antitoxin VapB-like

(1-81)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14150.21 Da        Isoelectric Point: 3.9777

>T80723 WP_096034424.1 NZ_CP023313:3701785-3702177 [Caulobacter vibrioides]
VTVVVDTSALMAIALDEPEADALIEALEAADDVVISPMTYVELGMVLLGRNLMPSRDDLDDWLALYRVEIAKAPVIDTAA
LDAYLRYGKGRNPARLNLSDCFAYALAKTLDAPLLYKGDDFSQTDIRSAL

Download         Length: 393 bp

>T80723 NZ_CP023313:3701785-3702177 [Caulobacter vibrioides]
GTGACGGTGGTCGTCGACACCTCGGCGCTCATGGCGATCGCCCTCGACGAACCCGAAGCCGACGCGCTGATAGAAGCGCT
TGAAGCGGCTGACGACGTCGTGATCTCGCCCATGACCTATGTCGAGCTGGGCATGGTGCTTCTTGGACGCAACCTGATGC
CGTCTCGCGATGATCTGGACGACTGGCTGGCCCTGTATCGCGTCGAGATCGCAAAGGCTCCCGTCATCGACACCGCCGCG
CTGGACGCCTACCTGCGCTACGGCAAAGGGCGAAACCCCGCACGGCTGAACCTGTCCGACTGTTTCGCCTACGCCCTGGC
CAAGACCCTGGACGCGCCCCTGCTCTACAAGGGCGACGACTTCAGCCAAACCGACATCCGCTCGGCGCTTTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10483.05 Da        Isoelectric Point: 6.3995

>AT80723 WP_096034423.1 NZ_CP023313:3701504-3701788 [Caulobacter vibrioides]
MGILIKNPEAERAVRELAELTGESLTTAVEIAVKERLAAKRAEAPPRRRRSVEEMKAITRKYLTPEARAGLLPPITQADY
DEINFIPGLDDRPS

Download         Length: 285 bp

>AT80723 NZ_CP023313:3701504-3701788 [Caulobacter vibrioides]
ATGGGCATCCTGATCAAGAACCCCGAGGCCGAGCGCGCCGTGCGCGAACTGGCGGAGCTGACCGGCGAGAGCTTGACCAC
AGCCGTCGAGATCGCGGTCAAGGAACGGCTGGCGGCCAAGCGGGCCGAGGCGCCGCCCCGTCGTCGTCGCAGCGTCGAAG
AGATGAAGGCGATTACCCGCAAGTATCTGACGCCCGAGGCGCGGGCCGGCCTGCTCCCGCCCATCACCCAGGCGGACTAC
GACGAGATCAACTTCATACCCGGCCTGGACGATCGCCCGTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References