Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/-
Location 3437149..3437591 Replicon chromosome
Accession NZ_CP023313
Organism Caulobacter vibrioides strain CB2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CA608_RS16750 Protein ID WP_205685753.1
Coordinates 3437316..3437591 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID P0CW75
Locus tag CA608_RS16745 Protein ID WP_012640671.1
Coordinates 3437149..3437328 (+) Length 60 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
- 3437149..3437328 + 180 - - Antitoxin
- 3437316..3437591 + 276 - - Toxin

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10141.74 Da        Isoelectric Point: 11.9574

>T80721 WP_205685753.1 NZ_CP023313:3437316-3437591 [Caulobacter vibrioides]
VAQVVWTQRAMADVYAIVGHISEQSRPLAAQRLAKRLFDTGASLATYPERGRVSTQGRREIVAISPYVLRYRIVGDRVVI
GSVRHGARRPL

Download         Length: 276 bp

>T80721 NZ_CP023313:3437316-3437591 [Caulobacter vibrioides]
GTGGCGCAAGTAGTCTGGACCCAACGAGCGATGGCCGATGTTTACGCCATCGTCGGCCATATCTCCGAGCAGTCGCGTCC
TCTCGCGGCCCAGCGCCTGGCCAAGAGGTTGTTCGACACCGGCGCTAGCCTGGCGACCTATCCCGAACGCGGGCGCGTGA
GCACTCAAGGACGGCGAGAGATCGTCGCGATTTCGCCCTACGTTCTGCGCTACCGCATTGTCGGCGACCGTGTCGTCATT
GGCAGCGTACGCCATGGGGCGCGTCGACCTCTCTAG

Antitoxin


Download         Length: 60 a.a.        Molecular weight: 6606.17 Da        Isoelectric Point: 3.9689

>AT80721 WP_012640671.1 NZ_CP023313:3437149-3437328 [Caulobacter vibrioides]
MAEPDPDIFDEDDEAILAADAEADADFEAGRTVPHERVGEWLKTLGTPHQTPPPYSWRK

Download         Length: 180 bp

>AT80721 NZ_CP023313:3437149-3437328 [Caulobacter vibrioides]
ATGGCCGAGCCTGACCCCGACATCTTCGACGAGGACGATGAAGCGATCCTGGCGGCTGACGCCGAGGCTGACGCCGACTT
CGAAGCCGGTAGAACTGTTCCGCACGAGCGTGTGGGCGAGTGGCTCAAGACGTTGGGCACGCCGCACCAGACACCGCCAC
CATATTCGTGGCGCAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB P0CW75

References