Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 952789..953324 Replicon chromosome
Accession NZ_CP023313
Organism Caulobacter vibrioides strain CB2

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag CA608_RS04535 Protein ID WP_096032676.1
Coordinates 952789..953076 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag CA608_RS04540 Protein ID WP_096032677.1
Coordinates 953073..953324 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CA608_RS04505 948476..949213 - 738 WP_124743107.1 hypothetical protein -
CA608_RS04510 949409..949999 - 591 WP_096032673.1 AAA family ATPase -
CA608_RS04515 949996..951063 - 1068 WP_164468079.1 serine hydrolase -
CA608_RS04520 951113..951289 - 177 WP_096032674.1 hypothetical protein -
CA608_RS04525 951368..951895 - 528 WP_096032675.1 GNAT family N-acetyltransferase -
CA608_RS04530 952027..952788 + 762 WP_096034735.1 MOSC N-terminal beta barrel domain-containing protein -
CA608_RS04535 952789..953076 - 288 WP_096032676.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CA608_RS04540 953073..953324 - 252 WP_096032677.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
CA608_RS04545 953424..954293 + 870 WP_096032678.1 peptide chain release factor N(5)-glutamine methyltransferase -
CA608_RS04550 954331..954555 + 225 WP_096032679.1 hypothetical protein -
CA608_RS04555 954552..955649 + 1098 WP_096032680.1 DUF4167 domain-containing protein -
CA608_RS04565 956001..956756 + 756 WP_096032682.1 M48 family metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-89)

Antitoxin

Antitoxin ParD

(4-72)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11029.52 Da        Isoelectric Point: 8.0582

>T80719 WP_096032676.1 NZ_CP023313:c953076-952789 [Caulobacter vibrioides]
VSAYRLTPRARYDVREIWAYTVGVWGRRAADRYIRELTKTFEAIAKDPSHGAIAEDLDCRKQIFRSHVIYYAPEDDAVIV
VRVLHQQMDAPSHLN

Download         Length: 288 bp

>T80719 NZ_CP023313:c953076-952789 [Caulobacter vibrioides]
GTGAGCGCCTATCGCCTGACGCCTCGCGCACGATACGACGTGCGCGAAATCTGGGCTTACACGGTCGGCGTCTGGGGACG
TCGCGCAGCGGACCGCTACATCCGTGAGCTTACCAAGACGTTCGAAGCGATCGCCAAGGATCCAAGCCACGGCGCGATCG
CGGAAGACCTGGACTGCCGCAAGCAGATCTTTCGCTCTCACGTCATCTACTACGCGCCCGAGGATGACGCGGTCATTGTG
GTTCGCGTCCTGCACCAGCAGATGGACGCGCCGAGCCACCTCAACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9150.16 Da        Isoelectric Point: 4.5052

>AT80719 WP_096032677.1 NZ_CP023313:c953324-953073 [Caulobacter vibrioides]
MSKNTSIVLSEHFQSFIAEKIEEGRYGSASEVVRAGLRLLENQEAKLAALRNALKEGWDSGKPEAFDVETFLAEANADYD
AKS

Download         Length: 252 bp

>AT80719 NZ_CP023313:c953324-953073 [Caulobacter vibrioides]
ATGAGCAAGAATACCTCCATCGTGCTCAGCGAGCACTTCCAGTCCTTCATCGCCGAGAAAATCGAGGAAGGTCGCTACGG
CTCGGCCAGCGAGGTCGTGCGCGCCGGACTGAGACTTCTGGAAAATCAGGAAGCCAAACTGGCCGCGCTGCGAAACGCCC
TGAAGGAGGGCTGGGACAGCGGCAAGCCCGAGGCCTTCGACGTGGAGACCTTTCTGGCGGAGGCGAACGCCGACTACGAC
GCCAAGTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References