Detailed information of TA system TA080718

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/-
• Location: 876976..877517
• Replicon: chromosome
• Accession: NZ_CP023313
• Organism: Caulobacter vibrioides strain CB2

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CA608_RS04155
• Protein ID: WP_096032620.1
• Coordinates: 876976..877257 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: CA608_RS04160
• Protein ID: WP_096032621.1
• Coordinates: 877254..877517 (-)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CA608_RS04140	872761..874341	-	1581	WP_164512754.1	carboxylesterase/lipase family protein	-
CA608_RS04145	874485..875570	+	1086	WP_205685769.1	cellulase family glycosylhydrolase	-
CA608_RS04150	875574..876899	-	1326	WP_096032619.1	cellulase family glycosylhydrolase	-
CA608_RS04155	876976..877257	-	282	WP_096032620.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CA608_RS04160	877254..877517	-	264	WP_096032621.1	type II toxin-antitoxin system antitoxin RelB1	Antitoxin
CA608_RS04165	877556..880645	-	3090	WP_096032622.1	bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase PutA	-
CA608_RS04170	880730..880891	+	162	WP_024265629.1	hypothetical protein	-
CA608_RS04175	881091..881558	+	468	WP_010918690.1	Lrp/AsnC ligand binding domain-containing protein	-
CA608_RS04180	881585..881749	-	165	WP_101685781.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-92)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10458.03 Da
• Isoelectric Point: 11.7926

>T80718 WP_096032620.1 NZ_CP023313:c877257-876976 [Caulobacter vibrioides]
VTFTVSVSVRAKRDFNRLIVWLVERDPRAAARLGPLLEAALDSLTEAPSRGRSVGPTTREISIPFGQSAYVIRYRLLGSS
VHVTRIWHSLEQR

Nucleotide

• Length: 282 bp

>T80718 NZ_CP023313:c877257-876976 [Caulobacter vibrioides]
GTGACCTTCACGGTCTCGGTGTCCGTCAGGGCCAAGAGAGACTTCAACCGTCTCATCGTCTGGCTTGTGGAGCGCGACCC
CCGAGCAGCGGCTAGACTGGGCCCACTTCTGGAGGCCGCCCTCGACAGTTTGACCGAGGCGCCATCGCGAGGTCGCTCGG
TTGGTCCCACCACCCGCGAGATCAGCATTCCTTTTGGTCAGAGCGCCTATGTGATCCGCTACCGGCTCCTCGGCTCCAGC
GTACATGTCACCCGGATCTGGCACAGCCTTGAGCAACGGTAG

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 9216.34 Da
• Isoelectric Point: 4.2560

>AT80718 WP_096032621.1 NZ_CP023313:c877517-877254 [Caulobacter vibrioides]
MADGFDIHIDQEQAARLKVVADRLGMSVSEYAVALIDAGLTGAAPKAIDPDPAIDEAIADAIERGDEPAISRDEFRAHMR
RVTAGLG

Nucleotide

• Length: 264 bp

>AT80718 NZ_CP023313:c877517-877254 [Caulobacter vibrioides]
ATGGCCGATGGCTTCGACATTCATATCGATCAAGAGCAGGCCGCCCGGCTGAAGGTCGTTGCCGACCGCCTGGGTATGTC
CGTGTCCGAGTACGCCGTTGCGCTGATCGACGCAGGCCTGACAGGCGCGGCGCCTAAAGCGATCGATCCGGACCCCGCCA
TCGACGAGGCCATCGCCGACGCCATCGAGCGGGGCGACGAGCCGGCGATTTCACGCGATGAGTTCCGCGCTCATATGCGT
CGCGTGACTGCGGGCCTGGGGTGA