Detailed information of TA system TA080706

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/PIN-MazE
• Location: 2677282..2677915
• Replicon: chromosome
• Accession: NZ_CP023285
• Organism: Xanthomonas citri pv. citri strain 03-1638-1-1

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: CLM98_RS12235
• Protein ID: WP_015463212.1
• Coordinates: 2677282..2677695 (-)
• Length: 138 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: M4TWF0
• Locus tag: CLM98_RS12240
• Protein ID: WP_015463213.1
• Coordinates: 2677682..2677915 (-)
• Length: 78 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CLM98_RS12220	2672974..2675154	+	2181	WP_011051394.1	TonB-dependent siderophore receptor	-
CLM98_RS12225	2675363..2676877	+	1515	WP_015463210.1	conjugal transfer protein TraG N-terminal domain-containing protein	-
CLM98_RS12230	2676893..2677255	-	363	WP_015463211.1	DUF3742 family protein	-
CLM98_RS12235	2677282..2677695	-	414	WP_015463212.1	PIN domain-containing protein	Toxin
CLM98_RS12240	2677682..2677915	-	234	WP_015463213.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
CLM98_RS12245	2678173..2679204	+	1032	WP_040107627.1	DUF4917 family protein	-
CLM98_RS12250	2679337..2679735	-	399	WP_099521978.1	hypothetical protein	-
CLM98_RS12255	2680187..2680762	+	576	WP_011051400.1	sigma-70 family RNA polymerase sigma factor	-
CLM98_RS12260	2680743..2681792	+	1050	WP_011051401.1	FecR domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (8-119)

Antitoxin

• SpoVT-AbrB domain (5-45)

Sequences

Toxin

Protein

• Length: 138 a.a.
• Molecular weight: 15221.65 Da
• Isoelectric Point: 6.3225

>T80706 WP_015463212.1 NZ_CP023285:c2677695-2677282 [Xanthomonas citri pv. citri]
MAAGKGKVFLDSNVVLYLLSEDAVKADGAEALLQRRPVISVQVLNEVTHVCVRKLKMGWDEVGQFLALVRSFCKIVPLTV
DVHDRARQLAERHQLSFYDACIVAAAAIEGCQTLYSEDMHHGLIIEESLSIRNPFNV

Nucleotide

• Length: 414 bp

>T80706 NZ_CP023285:c2677695-2677282 [Xanthomonas citri pv. citri]
ATGGCCGCGGGTAAGGGCAAAGTGTTTCTCGACAGCAACGTGGTGCTCTACCTGCTGTCGGAGGATGCGGTGAAGGCGGA
CGGCGCGGAGGCATTGCTGCAGCGCAGGCCCGTCATCAGTGTGCAGGTGCTCAATGAAGTGACCCACGTCTGCGTTCGCA
AGCTCAAGATGGGCTGGGACGAAGTCGGGCAGTTCCTTGCGTTGGTGCGATCGTTCTGCAAGATAGTGCCTCTGACGGTC
GATGTTCACGACCGTGCGCGCCAGCTGGCGGAGCGGCACCAATTGTCGTTCTACGACGCGTGCATCGTGGCGGCGGCCGC
CATCGAAGGGTGCCAGACCCTCTACTCCGAAGACATGCACCACGGCCTCATCATCGAAGAGAGCCTGTCGATTCGGAACC
CGTTCAACGTCTGA

Antitoxin

Protein

• Length: 78 a.a.
• Molecular weight: 8663.97 Da
• Isoelectric Point: 8.7848

>AT80706 WP_015463213.1 NZ_CP023285:c2677915-2677682 [Xanthomonas citri pv. citri]
MQVAKWGNSLAVRLPSSLVEALELREGDDIEIVVDDPRLFAVRKKPGPEAMLERLRAFRGKLPADFKFNRDEANGRG

Nucleotide

• Length: 234 bp

>AT80706 NZ_CP023285:c2677915-2677682 [Xanthomonas citri pv. citri]
ATGCAAGTCGCGAAGTGGGGTAACAGCCTGGCGGTGCGCCTGCCGTCCAGTCTGGTGGAAGCGCTGGAACTGCGCGAGGG
CGACGACATCGAGATCGTCGTCGATGATCCGCGATTGTTCGCGGTGCGCAAGAAGCCGGGTCCGGAGGCCATGTTGGAGC
GGCTGCGTGCCTTCCGGGGCAAGTTGCCCGCAGATTTCAAGTTCAACCGGGACGAGGCCAATGGCCGCGGGTAA

Structures

Antitoxin

• AlphaFold DB: M4TWF0