Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | phd-doc/HTH_IclR(antitoxin) |
Location | 3219356..3221095 | Replicon | chromosome |
Accession | NZ_CP023284 | ||
Organism | Variovorax boronicumulans strain J1 |
Toxin (Protein)
Gene name | doc | Uniprot ID | - |
Locus tag | CKY39_RS14750 | Protein ID | WP_095744976.1 |
Coordinates | 3219356..3220225 (+) | Length | 290 a.a. |
Antitoxin (Protein)
Gene name | phd | Uniprot ID | A0A554S243 |
Locus tag | CKY39_RS14755 | Protein ID | WP_070060330.1 |
Coordinates | 3220262..3221095 (+) | Length | 278 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CKY39_RS14725 | 3214455..3215423 | + | 969 | WP_157755232.1 | 2-dehydropantoate 2-reductase | - |
CKY39_RS14730 | 3215478..3216737 | + | 1260 | WP_095744974.1 | D-amino acid dehydrogenase | - |
CKY39_RS14735 | 3216929..3217912 | + | 984 | WP_062474573.1 | tripartite tricarboxylate transporter substrate binding protein | - |
CKY39_RS14740 | 3217990..3218748 | + | 759 | WP_185993640.1 | SDR family oxidoreductase | - |
CKY39_RS14745 | 3218792..3219328 | + | 537 | WP_062474577.1 | cupin domain-containing protein | - |
CKY39_RS14750 | 3219356..3220225 | + | 870 | WP_095744976.1 | alpha/beta hydrolase | Toxin |
CKY39_RS14755 | 3220262..3221095 | + | 834 | WP_070060330.1 | IclR family transcriptional regulator | Antitoxin |
CKY39_RS14760 | 3221116..3221955 | + | 840 | WP_095744977.1 | SDR family oxidoreductase | - |
CKY39_RS14765 | 3221948..3223645 | + | 1698 | WP_062474586.1 | thiamine pyrophosphate-binding protein | - |
CKY39_RS14770 | 3223666..3224466 | + | 801 | WP_062474588.1 | aspartate dehydrogenase | - |
CKY39_RS14775 | 3224475..3225950 | + | 1476 | WP_095744978.1 | aldehyde dehydrogenase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 290 a.a. Molecular weight: 29898.21 Da Isoelectric Point: 6.0184
>T80703 WP_095744976.1 NZ_CP023284:3219356-3220225 [Variovorax boronicumulans]
MSTVDISAQTLPASELARLDARFPARDVAVGGGAVVSVRECGQGPVIVCLHGIGSGAASWLDTAALLAPQACLIAWDAPG
YGRSTPLASAAPTAADYAARLEEMLDALSIRSCVLVGHSLGAIVAASAARSESSASERIRRLVLVSPAIGYGAAGRIDAR
AKVRAERLATLDDLGIAGMAAKRAGRLVSDGASEHARQWVRWNMARLNDHGYRQAVELLCNADLLADLPPPMPVRVACGA
LDVVTPPTACEEVARRCGVPLELVDDAGHAGYVEQPQAVAALLRESLAG
MSTVDISAQTLPASELARLDARFPARDVAVGGGAVVSVRECGQGPVIVCLHGIGSGAASWLDTAALLAPQACLIAWDAPG
YGRSTPLASAAPTAADYAARLEEMLDALSIRSCVLVGHSLGAIVAASAARSESSASERIRRLVLVSPAIGYGAAGRIDAR
AKVRAERLATLDDLGIAGMAAKRAGRLVSDGASEHARQWVRWNMARLNDHGYRQAVELLCNADLLADLPPPMPVRVACGA
LDVVTPPTACEEVARRCGVPLELVDDAGHAGYVEQPQAVAALLRESLAG
Download Length: 870 bp
>T80703 NZ_CP023284:3219356-3220225 [Variovorax boronicumulans]
ATGAGCACCGTCGACATCTCCGCGCAGACCCTGCCGGCTTCCGAGCTGGCGCGACTCGACGCGCGCTTTCCGGCCCGCGA
CGTCGCGGTGGGCGGCGGCGCGGTGGTGTCGGTGCGCGAATGCGGGCAGGGCCCGGTCATCGTGTGCCTGCACGGCATCG
GCTCGGGCGCGGCCTCGTGGCTCGACACCGCGGCGCTGCTGGCGCCGCAGGCCTGCCTCATCGCCTGGGATGCACCGGGC
TACGGCCGCTCGACGCCGCTGGCCTCGGCCGCGCCGACCGCCGCGGACTACGCCGCACGCCTTGAAGAAATGCTCGACGC
GCTGTCGATCCGCTCCTGCGTGCTCGTCGGCCATTCGCTGGGCGCCATCGTGGCCGCGTCGGCTGCGCGCAGCGAGTCGA
GCGCCAGTGAGCGCATCCGCCGCCTCGTGCTCGTGAGCCCCGCCATCGGCTACGGCGCCGCCGGGCGCATCGACGCCCGC
GCCAAGGTGCGCGCCGAACGCCTGGCCACGCTCGACGACCTCGGCATTGCCGGCATGGCCGCCAAGCGCGCGGGCCGGCT
CGTGTCCGACGGTGCCAGCGAACACGCCCGCCAGTGGGTGCGTTGGAACATGGCGCGTCTGAACGACCACGGCTACCGCC
AGGCCGTCGAGCTGCTGTGCAACGCCGACCTGCTGGCCGACCTGCCGCCGCCGATGCCCGTGCGCGTGGCCTGCGGCGCG
CTCGACGTCGTCACGCCGCCCACCGCCTGCGAAGAAGTCGCGCGCCGCTGCGGCGTGCCCCTCGAATTGGTGGACGATGC
GGGTCACGCCGGCTATGTGGAACAACCGCAGGCCGTCGCCGCCTTGCTGCGCGAATCGCTCGCCGGCTGA
ATGAGCACCGTCGACATCTCCGCGCAGACCCTGCCGGCTTCCGAGCTGGCGCGACTCGACGCGCGCTTTCCGGCCCGCGA
CGTCGCGGTGGGCGGCGGCGCGGTGGTGTCGGTGCGCGAATGCGGGCAGGGCCCGGTCATCGTGTGCCTGCACGGCATCG
GCTCGGGCGCGGCCTCGTGGCTCGACACCGCGGCGCTGCTGGCGCCGCAGGCCTGCCTCATCGCCTGGGATGCACCGGGC
TACGGCCGCTCGACGCCGCTGGCCTCGGCCGCGCCGACCGCCGCGGACTACGCCGCACGCCTTGAAGAAATGCTCGACGC
GCTGTCGATCCGCTCCTGCGTGCTCGTCGGCCATTCGCTGGGCGCCATCGTGGCCGCGTCGGCTGCGCGCAGCGAGTCGA
GCGCCAGTGAGCGCATCCGCCGCCTCGTGCTCGTGAGCCCCGCCATCGGCTACGGCGCCGCCGGGCGCATCGACGCCCGC
GCCAAGGTGCGCGCCGAACGCCTGGCCACGCTCGACGACCTCGGCATTGCCGGCATGGCCGCCAAGCGCGCGGGCCGGCT
CGTGTCCGACGGTGCCAGCGAACACGCCCGCCAGTGGGTGCGTTGGAACATGGCGCGTCTGAACGACCACGGCTACCGCC
AGGCCGTCGAGCTGCTGTGCAACGCCGACCTGCTGGCCGACCTGCCGCCGCCGATGCCCGTGCGCGTGGCCTGCGGCGCG
CTCGACGTCGTCACGCCGCCCACCGCCTGCGAAGAAGTCGCGCGCCGCTGCGGCGTGCCCCTCGAATTGGTGGACGATGC
GGGTCACGCCGGCTATGTGGAACAACCGCAGGCCGTCGCCGCCTTGCTGCGCGAATCGCTCGCCGGCTGA
Antitoxin
Download Length: 278 a.a. Molecular weight: 30605.96 Da Isoelectric Point: 5.7705
>AT80703 WP_070060330.1 NZ_CP023284:3220262-3221095 [Variovorax boronicumulans]
MATDNEVMEEGADRYNVPALERGLRVLCEFSRESRTLSAPELARRFDLPRSTVFRLLTTLENMGFLERAEGGRDYRLGLA
VLRLGFEYLASLELTQLGTPLLNRLCDELRTPCNLVVRDGRSIVYVAKVAPATPFASSVTVGTRLPAHATVLGRILLEDL
TLPQLRALYPEDKLETFSPSTPKTVNELFDMVQADRQRGYVLGEGFFESNISTIAAPVRDHSGHIVAALGATITSGHIDE
NRMDEMVQRVRGTADEISGLLNYSPARTSKVVPLRSA
MATDNEVMEEGADRYNVPALERGLRVLCEFSRESRTLSAPELARRFDLPRSTVFRLLTTLENMGFLERAEGGRDYRLGLA
VLRLGFEYLASLELTQLGTPLLNRLCDELRTPCNLVVRDGRSIVYVAKVAPATPFASSVTVGTRLPAHATVLGRILLEDL
TLPQLRALYPEDKLETFSPSTPKTVNELFDMVQADRQRGYVLGEGFFESNISTIAAPVRDHSGHIVAALGATITSGHIDE
NRMDEMVQRVRGTADEISGLLNYSPARTSKVVPLRSA
Download Length: 834 bp
>AT80703 NZ_CP023284:3220262-3221095 [Variovorax boronicumulans]
ATGGCCACCGACAACGAAGTGATGGAAGAGGGCGCGGACCGCTACAACGTGCCCGCGCTGGAGCGCGGCCTGCGCGTGCT
GTGCGAGTTCAGCCGCGAGAGCCGCACGCTGTCCGCGCCCGAGCTGGCGCGCCGCTTCGACCTGCCGCGCTCGACCGTCT
TCCGCCTGCTCACCACGCTGGAGAACATGGGTTTTCTCGAGCGCGCCGAGGGCGGACGCGACTACCGCCTGGGCCTGGCC
GTGCTGCGCCTGGGCTTCGAATACCTGGCCTCGCTGGAACTCACGCAACTGGGCACGCCGCTGCTCAACCGCCTGTGCGA
CGAGCTGCGCACGCCCTGCAACCTGGTGGTGCGCGACGGCCGCTCGATCGTCTACGTCGCCAAGGTGGCACCGGCCACGC
CCTTCGCCAGCTCGGTCACGGTGGGTACGCGCCTGCCGGCCCACGCCACGGTGCTGGGCCGCATCCTGCTGGAAGACCTC
ACGCTGCCGCAGCTGCGCGCGCTGTACCCCGAAGACAAGCTCGAGACCTTCTCGCCGAGCACGCCCAAGACCGTGAACGA
GCTCTTCGACATGGTGCAGGCCGACCGCCAGCGCGGCTATGTGCTGGGCGAGGGCTTCTTCGAATCGAACATCTCGACCA
TCGCCGCACCGGTGCGCGACCACAGCGGCCACATCGTGGCGGCACTGGGCGCCACCATCACCTCGGGCCACATCGACGAG
AACCGCATGGACGAGATGGTGCAGCGCGTGCGCGGCACCGCCGACGAGATCTCGGGCCTGCTCAATTACTCGCCCGCGCG
CACCAGCAAGGTGGTGCCGCTGCGCAGCGCCTGA
ATGGCCACCGACAACGAAGTGATGGAAGAGGGCGCGGACCGCTACAACGTGCCCGCGCTGGAGCGCGGCCTGCGCGTGCT
GTGCGAGTTCAGCCGCGAGAGCCGCACGCTGTCCGCGCCCGAGCTGGCGCGCCGCTTCGACCTGCCGCGCTCGACCGTCT
TCCGCCTGCTCACCACGCTGGAGAACATGGGTTTTCTCGAGCGCGCCGAGGGCGGACGCGACTACCGCCTGGGCCTGGCC
GTGCTGCGCCTGGGCTTCGAATACCTGGCCTCGCTGGAACTCACGCAACTGGGCACGCCGCTGCTCAACCGCCTGTGCGA
CGAGCTGCGCACGCCCTGCAACCTGGTGGTGCGCGACGGCCGCTCGATCGTCTACGTCGCCAAGGTGGCACCGGCCACGC
CCTTCGCCAGCTCGGTCACGGTGGGTACGCGCCTGCCGGCCCACGCCACGGTGCTGGGCCGCATCCTGCTGGAAGACCTC
ACGCTGCCGCAGCTGCGCGCGCTGTACCCCGAAGACAAGCTCGAGACCTTCTCGCCGAGCACGCCCAAGACCGTGAACGA
GCTCTTCGACATGGTGCAGGCCGACCGCCAGCGCGGCTATGTGCTGGGCGAGGGCTTCTTCGAATCGAACATCTCGACCA
TCGCCGCACCGGTGCGCGACCACAGCGGCCACATCGTGGCGGCACTGGGCGCCACCATCACCTCGGGCCACATCGACGAG
AACCGCATGGACGAGATGGTGCAGCGCGTGCGCGGCACCGCCGACGAGATCTCGGGCCTGCTCAATTACTCGCCCGCGCG
CACCAGCAAGGTGGTGCCGCTGCGCAGCGCCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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