Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 2252566..2253175 Replicon chromosome
Accession NZ_CP023278
Organism Nostoc sp. CENA543

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CLI64_RS09340 Protein ID WP_103136960.1
Coordinates 2252566..2252937 (-) Length 124 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CLI64_RS09345 Protein ID WP_103136961.1
Coordinates 2252930..2253175 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CLI64_RS09310 2248696..2249160 + 465 WP_103136954.1 hypothetical protein -
CLI64_RS09315 2249268..2249525 + 258 WP_103136955.1 hypothetical protein -
CLI64_RS09320 2249594..2250160 + 567 WP_103136956.1 cytochrome b -
CLI64_RS09325 2250228..2250806 - 579 WP_103136957.1 redoxin family protein -
CLI64_RS09330 2250899..2251444 - 546 WP_103136958.1 hypothetical protein -
CLI64_RS09335 2251431..2252549 - 1119 WP_103136959.1 ATP-binding protein -
CLI64_RS09340 2252566..2252937 - 372 WP_103136960.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CLI64_RS09345 2252930..2253175 - 246 WP_103136961.1 hypothetical protein Antitoxin
CLI64_RS09350 2253346..2255265 + 1920 WP_103136962.1 heavy metal translocating P-type ATPase -
CLI64_RS09355 2255262..2256401 + 1140 WP_103136963.1 FAD-binding oxidoreductase -
CLI64_RS09360 2256501..2256968 + 468 WP_103140658.1 hypothetical protein -
CLI64_RS09365 2256940..2257191 + 252 WP_103136964.1 hypothetical protein -
CLI64_RS09370 2257229..2257978 - 750 WP_103136965.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(30-109)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 14101.13 Da        Isoelectric Point: 9.1833

>T80701 WP_103136960.1 NZ_CP023278:c2252937-2252566 [Nostoc sp. CENA543]
MSEQPLIKVEATPTFNRNLRTLAKKYRSIRNDIKPVITQLEQGELPGEQISGIGYEVFKLRVRNTDIQKGKSGGYRLIYY
VKTAKGIILLTIYSKSEQTDIAADDIRRFIAEYEKSVDTDEEL

Download         Length: 372 bp

>T80701 NZ_CP023278:c2252937-2252566 [Nostoc sp. CENA543]
ATGTCTGAGCAACCATTGATTAAAGTTGAGGCTACACCAACTTTCAATCGCAATTTACGTACTCTGGCTAAAAAATATCG
CAGTATTCGTAATGATATAAAACCTGTAATTACACAACTTGAACAGGGAGAATTACCAGGAGAGCAGATATCTGGAATTG
GCTATGAAGTTTTTAAATTACGAGTACGAAATACTGACATTCAAAAAGGTAAAAGCGGCGGCTATCGTCTCATTTACTAT
GTAAAAACAGCAAAGGGAATTATTTTGCTGACTATTTATTCTAAATCTGAACAAACTGATATTGCAGCCGACGATATTAG
AAGATTCATTGCTGAGTATGAAAAATCTGTGGATACAGATGAAGAATTGTAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9216.48 Da        Isoelectric Point: 3.9944

>AT80701 WP_103136961.1 NZ_CP023278:c2253175-2252930 [Nostoc sp. CENA543]
MKAVKVMATIDENGQLTLDHPLMTDKNSRVEVIVLIPEIAEIDQPEQFQADIVEDFRQAWHEAMTGQTIPVTQLWEGLEN
V

Download         Length: 246 bp

>AT80701 NZ_CP023278:c2253175-2252930 [Nostoc sp. CENA543]
ATGAAAGCAGTTAAAGTCATGGCAACCATTGATGAAAATGGGCAACTTACTTTAGATCATCCCTTAATGACGGATAAAAA
TAGTCGCGTTGAAGTAATTGTTCTTATTCCTGAAATAGCAGAAATAGATCAACCAGAACAATTTCAAGCAGACATTGTAG
AAGATTTCCGTCAAGCTTGGCATGAAGCTATGACAGGACAAACAATCCCTGTAACTCAACTTTGGGAAGGATTGGAGAAT
GTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References