80689

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 5076852..5077894 Replicon chromosome
Accession NZ_CP023269
Organism Pseudomonas sp. MYb193

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag CLM72_RS23185 Protein ID WP_105228367.1
Coordinates 5076852..5077427 (-) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag CLM72_RS23190 Protein ID WP_054922011.1
Coordinates 5077424..5077894 (-) Length 157 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CLM72_RS23150 5072443..5072781 - 339 WP_003175975.1 preprotein translocase subunit YajC -
CLM72_RS23155 5072825..5073940 - 1116 WP_032803964.1 tRNA guanosine(34) transglycosylase Tgt -
CLM72_RS23160 5073946..5074995 - 1050 WP_105228363.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
CLM72_RS23170 5075272..5075601 + 330 WP_105228365.1 hypothetical protein -
CLM72_RS23175 5075609..5076244 - 636 WP_038451453.1 LysE family translocator -
CLM72_RS23180 5076400..5076771 + 372 WP_014719840.1 PH domain-containing protein -
CLM72_RS23185 5076852..5077427 - 576 WP_105228367.1 PIN domain-containing protein Toxin
CLM72_RS23190 5077424..5077894 - 471 WP_054922011.1 helix-turn-helix domain-containing protein Antitoxin
CLM72_RS23195 5078088..5079242 + 1155 WP_105228369.1 S-type pyocin domain-containing protein -
CLM72_RS23200 5079250..5079507 + 258 WP_105228371.1 colicin transporter -
CLM72_RS23205 5079566..5079844 + 279 Protein_4441 barstar family protein -
CLM72_RS23210 5080146..5081246 - 1101 WP_105229078.1 IS110 family transposase -
CLM72_RS23215 5081378..5081752 - 375 WP_034128041.1 cytochrome c family protein -
CLM72_RS23220 5081783..5082214 - 432 WP_105228373.1 VOC family protein -
CLM72_RS23225 5082377..5082739 + 363 WP_003194033.1 response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-115)

Antitoxin

Helix-turn-helix domain, group 17

(84-132)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21433.83 Da        Isoelectric Point: 4.7036

>T80689 WP_105228367.1 NZ_CP023269:c5077427-5076852 [Pseudomonas sp. MYb193]
MRCSPFTAVYDACVLYPAVLRDLLMWLGLSGLYRARWTSQIQDEWKRNILKNRPDLTAAQVDCTSALMDVAIPDALVTGY
EDLCSSLDLPDPDDRHVLAAAIRSKAEVIVTFNLKDFPPHILAAYDIEPMHPDDFISDLWDLDQAAVLGAAQKQRRALKK
PAMEAGSYLEMLMRQGLVQTSKAMGPYEMML

Download         Length: 576 bp

>T80689 NZ_CP023269:c5077427-5076852 [Pseudomonas sp. MYb193]
ATGAGGTGTTCGCCCTTTACAGCGGTATACGACGCTTGTGTTCTCTATCCTGCGGTTCTTCGGGACTTACTCATGTGGCT
TGGTTTGTCTGGGTTATATCGAGCGCGATGGACTAGCCAGATTCAGGATGAGTGGAAGCGCAACATACTCAAGAATCGAC
CCGATCTTACGGCCGCGCAGGTGGACTGCACGTCGGCGCTAATGGACGTTGCGATACCTGACGCTCTGGTGACCGGATAT
GAGGACCTGTGTTCGAGTTTGGATTTACCAGACCCGGATGACCGGCATGTGTTGGCGGCAGCAATTCGGAGTAAAGCTGA
GGTTATCGTGACCTTCAATTTGAAAGACTTTCCACCACATATATTGGCTGCCTATGACATTGAACCGATGCATCCGGATG
ACTTTATTTCGGATCTCTGGGATTTGGATCAGGCGGCAGTTTTGGGAGCAGCGCAGAAGCAGAGGAGGGCGTTGAAGAAG
CCCGCGATGGAGGCGGGAAGCTATCTCGAAATGTTGATGCGGCAGGGCTTGGTGCAGACTAGCAAGGCAATGGGGCCTTA
TGAAATGATGCTGTGA

Antitoxin


Download         Length: 157 a.a.        Molecular weight: 17482.15 Da        Isoelectric Point: 6.1085

>AT80689 WP_054922011.1 NZ_CP023269:c5077894-5077424 [Pseudomonas sp. MYb193]
MTINNLPKTILPLEKEVEAAVQGQRELASLLSTKFETQRIDIFDKEDKPHRLVLPTSALRLLVDILGELALGNAVKVVPV
HAELTSQEAADLLNVSRPHLVKMLEDGAIPFTKTGRHRRVRFSDLMAFKQRRDEQSQEAMEALVQQAQELGMGYDG

Download         Length: 471 bp

>AT80689 NZ_CP023269:c5077894-5077424 [Pseudomonas sp. MYb193]
ATGACCATAAACAATCTTCCCAAAACGATCCTTCCGCTGGAAAAAGAAGTCGAGGCGGCAGTGCAGGGCCAGCGTGAATT
AGCGTCCCTATTGTCGACCAAATTTGAAACCCAGCGCATCGACATCTTCGACAAAGAAGATAAGCCACACAGGCTTGTAC
TCCCAACCTCCGCACTGCGCCTGCTGGTCGATATTCTGGGCGAATTGGCGCTCGGCAATGCCGTCAAGGTAGTGCCGGTT
CATGCCGAGTTGACCTCGCAGGAGGCGGCCGACTTGCTTAATGTGTCACGCCCGCATTTGGTCAAAATGCTGGAGGACGG
CGCTATCCCCTTTACAAAAACGGGTCGACATCGTCGAGTCCGCTTTTCGGATTTGATGGCCTTCAAGCAACGGCGTGACG
AGCAAAGCCAAGAGGCAATGGAAGCGCTGGTTCAACAGGCCCAAGAGTTGGGAATGGGGTATGACGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References