Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parE_1-relB/RelE(toxin)
Location 3572979..3573448 Replicon chromosome
Accession NZ_CP023269
Organism Pseudomonas sp. MYb193

Toxin (Protein)


Gene name parE_1 Uniprot ID -
Locus tag CLM72_RS16090 Protein ID WP_105227130.1
Coordinates 3572979..3573254 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CLM72_RS16095 Protein ID WP_105227131.1
Coordinates 3573254..3573448 (-) Length 65 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CLM72_RS16070 3568427..3568858 + 432 WP_105227126.1 hypothetical protein -
CLM72_RS16075 3569308..3570426 - 1119 WP_105227127.1 carboxylate-amine ligase -
CLM72_RS16080 3570434..3571378 - 945 WP_105227128.1 class I SAM-dependent methyltransferase -
CLM72_RS16085 3571390..3572769 - 1380 WP_105227129.1 iron-containing redox enzyme family protein -
CLM72_RS16090 3572979..3573254 - 276 WP_105227130.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CLM72_RS16095 3573254..3573448 - 195 WP_105227131.1 stability determinant Antitoxin
CLM72_RS16100 3573592..3575334 - 1743 WP_003192009.1 ABC transporter substrate-binding protein -
CLM72_RS16105 3575383..3575655 - 273 WP_014718862.1 DUF2160 domain-containing protein -
CLM72_RS16110 3575667..3576467 - 801 WP_003232361.1 carbohydrate ABC transporter permease -
CLM72_RS16115 3576478..3577344 - 867 WP_105227132.1 sugar ABC transporter permease -
CLM72_RS16120 3577341..3578438 - 1098 WP_105227133.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10334.92 Da        Isoelectric Point: 5.5976

>T80688 WP_105227130.1 NZ_CP023269:c3573254-3572979 [Pseudomonas sp. MYb193]
MLSVVWLDEAISDLIDIVTFIAEENPGAARRIKTRLEGAPLPLTEHPYLYPNGRVPGTREVVVHPNYVLVYRVTAERIEI
VSVLHARQEYP

Download         Length: 276 bp

>T80688 NZ_CP023269:c3573254-3572979 [Pseudomonas sp. MYb193]
ATGTTAAGCGTTGTTTGGCTTGATGAGGCTATCAGCGACCTGATTGACATCGTTACTTTCATTGCAGAAGAGAATCCTGG
AGCGGCGCGACGTATCAAGACACGTCTTGAAGGTGCGCCTCTGCCACTGACCGAGCATCCTTACCTGTATCCGAACGGCC
GTGTGCCCGGTACGCGGGAGGTCGTCGTTCACCCCAATTACGTCCTGGTGTATCGAGTAACAGCAGAGCGCATCGAGATA
GTCAGCGTGTTGCACGCTCGGCAAGAGTATCCCTGA

Antitoxin


Download         Length: 65 a.a.        Molecular weight: 7111.08 Da        Isoelectric Point: 5.0509

>AT80688 WP_105227131.1 NZ_CP023269:c3573448-3573254 [Pseudomonas sp. MYb193]
MGVPLSPIVSEFETEEQANSHDLWFRAKVEKSLANPGPGVPHDEVMARVEAIILEAERKQRAKA

Download         Length: 195 bp

>AT80688 NZ_CP023269:c3573448-3573254 [Pseudomonas sp. MYb193]
ATGGGTGTTCCACTTTCCCCAATTGTTTCCGAATTTGAAACCGAGGAGCAGGCAAATAGTCATGATCTTTGGTTTCGCGC
CAAAGTCGAAAAAAGCTTGGCCAATCCCGGACCCGGTGTACCCCATGACGAAGTCATGGCGAGGGTCGAGGCGATTATCC
TTGAAGCAGAACGTAAGCAGAGGGCCAAAGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References