80686

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3993614..3994280 Replicon chromosome
Accession NZ_CP023268
Organism Serratia sp. MYb239

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag CLM71_RS19120 Protein ID WP_105232394.1
Coordinates 3993614..3994033 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag CLM71_RS19125 Protein ID WP_105232395.1
Coordinates 3994014..3994280 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CLM71_RS19100 3989587..3991317 - 1731 WP_105232391.1 single-stranded-DNA-specific exonuclease RecJ -
CLM71_RS19105 3991330..3992046 - 717 WP_015673664.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
CLM71_RS19110 3992074..3992973 - 900 WP_105232392.1 site-specific tyrosine recombinase XerD -
CLM71_RS19115 3993065..3993583 + 519 WP_105232393.1 flavodoxin FldB -
CLM71_RS19120 3993614..3994033 - 420 WP_105232394.1 hypothetical protein Toxin
CLM71_RS19125 3994014..3994280 - 267 WP_105232395.1 FAD assembly factor SdhE Antitoxin
CLM71_RS19130 3994611..3995603 + 993 WP_105232396.1 tRNA-modifying protein YgfZ -
CLM71_RS19135 3995640..3996320 - 681 WP_105232397.1 hemolysin III family protein -
CLM71_RS19140 3996515..3997123 + 609 WP_105232398.1 HD domain-containing protein -
CLM71_RS19145 3997157..3998476 - 1320 WP_105232399.1 MHS family MFS transporter -
CLM71_RS19150 3998473..3999126 - 654 WP_105232400.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 16481.54 Da        Isoelectric Point: 11.5037

>T80686 WP_105232394.1 NZ_CP023268:c3994033-3993614 [Serratia sp. MYb239]
VAQWRCDVRISWRTQLISLLAHGALILLILISPWPESYDPVWLLLLTLVVFECIRSQTRIASRQGELRLLSAPQRVIWQG
KEWRLVRRPWMLRYGMLLTLQASGKRKRRRLWLASDCISSAEWRQLCQRMRLVKDESEG

Download         Length: 420 bp

>T80686 NZ_CP023268:c3994033-3993614 [Serratia sp. MYb239]
GTGGCCCAGTGGCGATGTGATGTCCGCATCTCCTGGCGTACTCAGCTTATCTCGTTGTTGGCGCATGGCGCGCTGATATT
GCTGATCCTGATTTCGCCGTGGCCGGAGAGTTACGATCCGGTCTGGCTATTGCTGCTGACGCTGGTGGTTTTTGAATGTA
TTCGCAGTCAGACGCGTATCGCATCGCGCCAGGGGGAGTTGCGCCTGCTCTCTGCGCCGCAGCGGGTAATCTGGCAAGGC
AAGGAGTGGCGGCTGGTCCGGCGCCCATGGATGCTGCGCTATGGCATGCTGCTGACGCTGCAGGCGAGCGGAAAGCGTAA
ACGCCGGCGGCTGTGGCTGGCGTCGGACTGCATCAGCAGTGCGGAGTGGCGGCAGTTGTGCCAGCGGATGCGGCTGGTCA
AGGATGAATCTGAAGGCTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10405.90 Da        Isoelectric Point: 5.0964

>AT80686 WP_105232395.1 NZ_CP023268:c3994280-3994014 [Serratia sp. MYb239]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSEEDKALFVRLLQCDDPDLFNWLMNHGAPQDAELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT80686 NZ_CP023268:c3994280-3994014 [Serratia sp. MYb239]
ATGGATATTAATAACAAAGCGCGTATTCACTGGGCTTGCCGCCGTGGAATGCGTGAGCTGGACATCTCCATCATGCCGTT
TTTCGAGCATGAGTACGATTCATTGAGCGAAGAGGATAAGGCGCTGTTCGTGCGTTTGTTGCAGTGTGACGATCCCGATC
TGTTTAACTGGCTGATGAATCATGGCGCCCCGCAGGACGCTGAATTGCAAAGAATGGTGACGCTGATCCAGACGCGAAAT
AAAGACCGTGGCCCAGTGGCGATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References