Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 670676..670821 Replicon chromosome
Accession NZ_CP023249
Organism Klebsiella pneumoniae strain CCUG 70742

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 670712..670814 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 670676..670821 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CLH64_RS03170 665806..667866 + 2061 WP_004151449.1 oligopeptidase B -
CLH64_RS03175 667870..668529 - 660 WP_002911407.1 exodeoxyribonuclease X -
CLH64_RS03180 668608..668838 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CLH64_RS03185 668951..669325 + 375 WP_039819395.1 CopC domain-containing protein YobA -
CLH64_RS03190 669329..670198 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
CLH64_RS03195 670215..670553 + 339 WP_002911404.1 YebY family protein -
- 670676..670821 - 146 - - Antitoxin
- 670712..670814 + 103 - - Toxin
CLH64_RS27305 671190..671333 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
CLH64_RS03205 671438..672406 - 969 WP_014907334.1 VirK/YbjX family protein -
CLH64_RS03210 672563..673216 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
CLH64_RS03215 673213..673404 - 192 WP_002911395.1 YebW family protein -
CLH64_RS03220 673502..673741 - 240 WP_002911393.1 YebV family protein -
CLH64_RS03225 673857..675290 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T80646 NZ_CP023249:670712-670814 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT80646 NZ_CP023249:c670821-670676 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References