Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 68399..68922 Replicon plasmid unnamed2
Accession NZ_CP023206
Organism Burkholderia glumae strain 336gr-1

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag CG017_RS29475 Protein ID WP_035979129.1
Coordinates 68399..68665 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CG017_RS29480 Protein ID WP_035979131.1
Coordinates 68662..68922 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CG017_RS29440 (CG017_05793) 65208..65417 - 210 WP_035979706.1 hypothetical protein -
CG017_RS29445 (CG017_05794) 65414..66094 - 681 WP_254613398.1 hypothetical protein -
CG017_RS29450 (CG017_05795) 66119..66451 - 333 WP_035982304.1 H-NS histone family protein -
CG017_RS29455 (CG017_05796) 66562..66855 - 294 WP_173941335.1 DUF6388 family protein -
CG017_RS29460 (CG017_05797) 66891..67085 - 195 WP_173941336.1 hypothetical protein -
CG017_RS29465 67082..67405 - 324 WP_173941337.1 hypothetical protein -
CG017_RS29470 (CG017_05798) 67675..68253 - 579 WP_173941338.1 YkgJ family cysteine cluster protein -
CG017_RS29475 (CG017_05799) 68399..68665 - 267 WP_035979129.1 Txe/YoeB family addiction module toxin Toxin
CG017_RS29480 (CG017_05800) 68662..68922 - 261 WP_035979131.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CG017_RS29485 (CG017_05801) 69116..70939 - 1824 WP_173941339.1 site-specific integrase -
CG017_RS29490 (CG017_05802) 70936..71316 - 381 WP_173941340.1 hypothetical protein -
CG017_RS29495 (CG017_05803) 71351..71668 - 318 WP_017433735.1 hypothetical protein -
CG017_RS29500 (CG017_05804) 71731..72141 - 411 WP_039203971.1 type II toxin-antitoxin system VapC family toxin -
CG017_RS29505 (CG017_05805) 72132..72386 - 255 WP_012734091.1 antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..135963 135963


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(9-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10412.81 Da        Isoelectric Point: 7.9846

>T80633 WP_035979129.1 NZ_CP023206:c68665-68399 [Burkholderia glumae]
MSGALNIMWTAEAWDDYVYWQGQDKKTIKRINQLIRDTQRSPFEGIGKPEPLKENLTGFWSRRIDETSRLVYEIAGTQIN
IISCRYHY

Download         Length: 267 bp

>T80633 NZ_CP023206:c68665-68399 [Burkholderia glumae]
ATGAGCGGCGCATTGAACATCATGTGGACGGCCGAGGCATGGGACGACTATGTTTACTGGCAGGGGCAGGACAAAAAAAC
GATAAAGCGCATCAATCAGCTCATTAGGGATACGCAACGCTCACCGTTCGAGGGAATCGGGAAACCGGAGCCATTAAAGG
AAAATCTGACGGGTTTTTGGTCACGCCGCATCGATGAGACGAGTCGTCTAGTCTACGAAATCGCTGGCACGCAGATCAAC
ATCATCTCGTGCCGCTACCACTACTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9648.02 Da        Isoelectric Point: 7.3196

>AT80633 WP_035979131.1 NZ_CP023206:c68922-68662 [Burkholderia glumae]
MRTIPFSDARANLKRVIDQVVDDVDVTLITRRDAPNAVVMSQEHYDSLMETVHLLRSPANVAHLERSIAQARAGKVKPRK
LVDDGE

Download         Length: 261 bp

>AT80633 NZ_CP023206:c68922-68662 [Burkholderia glumae]
ATGCGAACCATTCCTTTTTCGGACGCCCGCGCCAATCTCAAGCGGGTCATCGACCAAGTGGTCGACGACGTAGACGTCAC
GCTTATTACGCGACGCGACGCACCGAACGCGGTCGTCATGTCTCAAGAGCATTATGACAGCTTGATGGAGACGGTTCACC
TGTTGCGCTCGCCGGCGAACGTCGCCCATTTGGAACGCTCGATCGCACAGGCTAGAGCAGGCAAAGTGAAACCCCGTAAG
CTGGTTGACGACGGCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References