Detailed information of TA system TA080612

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 161100..161482
• Replicon: plasmid pSH1
• Accession: NZ_CP023190
• Organism: Acetobacter pomorum strain SH

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CJF59_RS15295
• Protein ID: WP_081939029.1
• Coordinates: 161327..161482 (+)
• Length: 52 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: CJF59_RS15290
• Protein ID: WP_116100447.1
• Coordinates: 161100..161342 (+)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CJF59_RS15260	156322..157401	+	1080	WP_089178403.1	IS5 family transposase	-
CJF59_RS15265	157508..157717	-	210	WP_116100445.1	glycosyltransferase	-
CJF59_RS15270	157745..158443	-	699	WP_116100446.1	thymidylate kinase	-
CJF59_RS15275	158864..159070	-	207	Protein_179	IS5/IS1182 family transposase	-
CJF59_RS15280	159168..159419	+	252	Protein_180	transposase	-
CJF59_RS15290	161100..161342	+	243	WP_116100447.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
CJF59_RS15295	161327..161482	+	156	WP_081939029.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CJF59_RS15300	161485..162570	+	1086	WP_116100448.1	hypothetical protein	-
CJF59_RS15305	162583..163629	-	1047	WP_116100449.1	Fic family protein	-
CJF59_RS15310	163626..163919	-	294	WP_003626805.1	hypothetical protein	-
CJF59_RS15315	164073..165392	-	1320	WP_116100371.1	replication protein C	-
CJF59_RS15325	166148..166426	-	279	WP_116100450.1	DUF2312 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..166956	166956

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-39)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-69)

Sequences

Toxin

Protein

• Length: 52 a.a.
• Molecular weight: 5850.79 Da
• Isoelectric Point: 10.5191

>T80612 WP_081939029.1 NZ_CP023190:161327-161482 [Acetobacter pomorum]
IGRSVSCYKIKRRASGYRLVYQVHEGKLIVLVVAIGRRDANEVYDDATRRV

Nucleotide

• Length: 156 bp

>T80612 NZ_CP023190:161327-161482 [Acetobacter pomorum]
ATTGGACGATCTGTGAGCTGCTATAAAATCAAACGTCGAGCTTCCGGATATCGGCTGGTGTATCAGGTTCATGAGGGGAA
ACTCATAGTGCTGGTTGTTGCGATTGGACGCAGGGATGCCAATGAGGTTTACGACGATGCAACCCGCCGCGTCTGA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 8764.05 Da
• Isoelectric Point: 4.5258

>AT80612 WP_116100447.1 NZ_CP023190:161100-161342 [Acetobacter pomorum]
MASINLRIDDSLKKAAYDRLSELGVTSSDLIRQTVEYVVATGKLPVRRTVVSDDGLELLPVVRERLASPEPSIPVSLDDL

Nucleotide

• Length: 243 bp

>AT80612 NZ_CP023190:161100-161342 [Acetobacter pomorum]
ATGGCTTCAATTAACCTGCGCATCGATGACAGTCTGAAGAAAGCTGCATACGATCGTCTGTCAGAACTCGGCGTGACATC
CTCAGATCTTATCCGCCAGACCGTTGAATATGTCGTCGCTACTGGCAAGCTCCCTGTCCGGCGCACTGTTGTATCGGATG
ACGGTCTGGAGCTTCTTCCCGTCGTTCGAGAGCGTCTTGCCTCGCCTGAACCGTCTATTCCGGTTTCATTGGACGATCTG
TGA