Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 10987..11539 Replicon plasmid pSH1
Accession NZ_CP023190
Organism Acetobacter pomorum strain SH

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CJF59_RS14400 Protein ID WP_116100453.1
Coordinates 11249..11539 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CJF59_RS14395 Protein ID WP_116100355.1
Coordinates 10987..11232 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CJF59_RS14365 6357..7532 - 1176 WP_116100351.1 hypothetical protein -
CJF59_RS14370 7532..8095 - 564 WP_116100352.1 hypothetical protein -
CJF59_RS14380 8503..8682 - 180 WP_086897492.1 hypothetical protein -
CJF59_RS14385 9188..10015 + 828 WP_116100354.1 helix-turn-helix domain-containing protein -
CJF59_RS14390 10054..10848 + 795 Protein_9 IS5 family transposase -
CJF59_RS14395 10987..11232 + 246 WP_116100355.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
CJF59_RS14400 11249..11539 + 291 WP_116100453.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
CJF59_RS14405 11567..12424 - 858 WP_116100356.1 hypothetical protein -
CJF59_RS14410 12492..12977 - 486 WP_162870756.1 hypothetical protein -
CJF59_RS14415 13049..13845 + 797 Protein_14 IS5 family transposase -
CJF59_RS14420 14066..14254 - 189 Protein_15 IS5/IS1182 family transposase -
CJF59_RS14425 14353..14712 + 360 WP_007400224.1 transposase -
CJF59_RS14430 14709..14960 + 252 WP_116100358.1 IS66 family insertion sequence element accessory protein TnpB -
CJF59_RS14435 14997..16076 + 1080 WP_116100359.1 IS5 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..166956 166956
- inside IScluster/Tn - - 10054..14960 4906


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type II bacterial toxin-antitoxin system, ParE-like toxin

(10-87)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-69)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11288.27 Da        Isoelectric Point: 10.3602

>T80609 WP_116100453.1 NZ_CP023190:11249-11539 [Acetobacter pomorum]
IEYGIEFSISAKKEWDRLSGDIKKQFKKKLDKLRYDPYSAPRLRGDLHGLFKVKLKSSGFRMVYQVIDNEIIILILGIGK
RNNDDIYTSMKNMKIF

Download         Length: 291 bp

>T80609 NZ_CP023190:11249-11539 [Acetobacter pomorum]
ATTGAATATGGGATTGAATTTTCTATATCCGCAAAGAAAGAATGGGATAGATTATCGGGCGATATAAAGAAGCAGTTCAA
GAAGAAATTAGATAAATTACGTTATGATCCATATTCAGCACCAAGATTGAGAGGTGATCTACATGGATTGTTCAAGGTAA
AGCTTAAATCATCTGGTTTTAGAATGGTTTATCAGGTCATAGATAATGAAATTATCATATTAATTCTTGGAATTGGTAAA
CGTAACAATGATGATATCTATACCTCAATGAAGAATATGAAGATATTTTAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9446.06 Da        Isoelectric Point: 8.4591

>AT80609 WP_116100355.1 NZ_CP023190:10987-11232 [Acetobacter pomorum]
MSGTAQISLKVDQDLKKEAYDKLKKLGVKPSEFFRDMLEYVVKENKLPVSKEIISADDMELLMLAKERINEKRVRVQFND
L

Download         Length: 246 bp

>AT80609 NZ_CP023190:10987-11232 [Acetobacter pomorum]
ATGTCTGGGACAGCGCAGATTAGCTTGAAGGTTGATCAGGATTTAAAGAAGGAAGCATATGATAAGCTGAAGAAGCTAGG
TGTAAAGCCAAGTGAATTTTTCAGAGATATGCTGGAGTATGTTGTGAAAGAAAACAAACTCCCGGTTTCAAAAGAAATTA
TATCCGCCGATGATATGGAGTTGTTAATGCTGGCGAAAGAACGCATTAATGAAAAACGAGTGCGCGTCCAGTTTAATGAC
CTCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References