Detailed information of TA system
Overview
TA module
Type | II | Classification (family/domain) | ccdAB/CcdA(antitoxin) |
Location | 2695013..2695560 | Replicon | chromosome |
Accession | NZ_CP023185 | ||
Organism | Klebsiella michiganensis strain K518 |
Toxin (Protein)
Gene name | ccdB | Uniprot ID | - |
Locus tag | CKQ55_RS13355 | Protein ID | WP_014839830.1 |
Coordinates | 2695013..2695321 (-) | Length | 103 a.a. |
Antitoxin (Protein)
Gene name | ccdA | Uniprot ID | A0A0H3H0P7 |
Locus tag | CKQ55_RS13360 | Protein ID | WP_014227298.1 |
Coordinates | 2695324..2695560 (-) | Length | 79 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CKQ55_RS13325 | 2690660..2690971 | - | 312 | WP_014839834.1 | PTS sugar transporter subunit IIB | - |
CKQ55_RS13330 | 2691266..2692207 | + | 942 | WP_014227303.1 | LacI family transcriptional regulator | - |
CKQ55_RS13335 | 2692231..2692524 | - | 294 | WP_014227302.1 | hypothetical protein | - |
CKQ55_RS13340 | 2692734..2693699 | + | 966 | WP_014839832.1 | Rpn family recombination-promoting nuclease/putative transposase | - |
CKQ55_RS13345 | 2693699..2693956 | + | 258 | WP_038422923.1 | hypothetical protein | - |
CKQ55_RS13350 | 2693960..2694862 | - | 903 | WP_014227300.1 | EamA family transporter | - |
CKQ55_RS13355 | 2695013..2695321 | - | 309 | WP_014839830.1 | CcdB family protein | Toxin |
CKQ55_RS13360 | 2695324..2695560 | - | 237 | WP_014227298.1 | type II toxin-antitoxin system CcdA family antitoxin | Antitoxin |
CKQ55_RS13365 | 2695666..2697099 | - | 1434 | WP_014839829.1 | PTS N-acetylmuramic acid transporter subunit IIBC | - |
CKQ55_RS13370 | 2697124..2698026 | - | 903 | WP_009654080.1 | N-acetylmuramic acid 6-phosphate etherase | - |
CKQ55_RS13375 | 2698187..2699353 | - | 1167 | WP_014839828.1 | multidrug effflux MFS transporter | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 a.a. Molecular weight: 11724.63 Da Isoelectric Point: 8.8012
>T80594 WP_014839830.1 NZ_CP023185:c2695321-2695013 [Klebsiella michiganensis]
MQYYVYKNTGRIAAYPYLLDVQSDIIGKRNTRVVIPLFPLKNYKGPRADRLTPLVTVEGEEYVVMTHELASIPHRVLGKE
VCNLNHQREVVKASMDFLFDGI
MQYYVYKNTGRIAAYPYLLDVQSDIIGKRNTRVVIPLFPLKNYKGPRADRLTPLVTVEGEEYVVMTHELASIPHRVLGKE
VCNLNHQREVVKASMDFLFDGI
Download Length: 309 bp
>T80594 NZ_CP023185:c2695321-2695013 [Klebsiella michiganensis]
ATGCAGTATTACGTTTATAAGAATACAGGTCGAATTGCTGCGTATCCTTACCTCCTTGATGTACAGAGTGACATTATCGG
CAAGCGCAATACTCGGGTCGTGATTCCACTGTTTCCACTGAAAAACTATAAAGGCCCACGCGCCGATCGTTTAACACCGC
TTGTCACCGTAGAAGGGGAAGAATACGTCGTGATGACTCACGAACTCGCCAGCATCCCACATCGTGTTCTGGGTAAAGAA
GTTTGTAATCTGAATCACCAGCGCGAAGTCGTTAAAGCTTCAATGGATTTTCTTTTCGACGGGATCTAA
ATGCAGTATTACGTTTATAAGAATACAGGTCGAATTGCTGCGTATCCTTACCTCCTTGATGTACAGAGTGACATTATCGG
CAAGCGCAATACTCGGGTCGTGATTCCACTGTTTCCACTGAAAAACTATAAAGGCCCACGCGCCGATCGTTTAACACCGC
TTGTCACCGTAGAAGGGGAAGAATACGTCGTGATGACTCACGAACTCGCCAGCATCCCACATCGTGTTCTGGGTAAAGAA
GTTTGTAATCTGAATCACCAGCGCGAAGTCGTTAAAGCTTCAATGGATTTTCTTTTCGACGGGATCTAA
Antitoxin
Download Length: 79 a.a. Molecular weight: 8783.92 Da Isoelectric Point: 5.7928
>AT80594 WP_014227298.1 NZ_CP023185:c2695560-2695324 [Klebsiella michiganensis]
MPAAKRNKQNVSVTLDPGLVKQAREVGINLSLTLTNALKSEIHSLEIARWQKENAQAIDYLNNLTEENGLLSDEYRTF
MPAAKRNKQNVSVTLDPGLVKQAREVGINLSLTLTNALKSEIHSLEIARWQKENAQAIDYLNNLTEENGLLSDEYRTF
Download Length: 237 bp
>AT80594 NZ_CP023185:c2695560-2695324 [Klebsiella michiganensis]
ATGCCAGCCGCAAAACGCAATAAGCAGAACGTCAGCGTGACACTGGACCCAGGCCTGGTCAAACAGGCTCGTGAGGTCGG
CATCAATCTGTCTCTAACGTTGACTAACGCTCTAAAAAGCGAAATCCACAGCCTCGAAATAGCCCGCTGGCAAAAAGAAA
ATGCCCAGGCAATCGACTACCTCAATAATTTAACTGAGGAAAATGGACTTCTCTCTGATGAATACAGGACGTTCTAA
ATGCCAGCCGCAAAACGCAATAAGCAGAACGTCAGCGTGACACTGGACCCAGGCCTGGTCAAACAGGCTCGTGAGGTCGG
CATCAATCTGTCTCTAACGTTGACTAACGCTCTAAAAAGCGAAATCCACAGCCTCGAAATAGCCCGCTGGCAAAAAGAAA
ATGCCCAGGCAATCGACTACCTCAATAATTTAACTGAGGAAAATGGACTTCTCTCTGATGAATACAGGACGTTCTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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