Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ypjF-yeeU/CbtA-CbeA
Location 2962853..2963586 Replicon chromosome
Accession NZ_CP023184
Organism Yersinia ruckeri strain NHV_3758

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag CLC90_RS13675 Protein ID WP_096823575.1
Coordinates 2963257..2963586 (+) Length 110 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag CLC90_RS13670 Protein ID WP_096823574.1
Coordinates 2962853..2963218 (+) Length 122 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CLC90_RS13625 2958148..2958849 + 702 WP_050297207.1 WYL domain-containing protein -
CLC90_RS13630 2958855..2959421 + 567 WP_096823569.1 hypothetical protein -
CLC90_RS13635 2959460..2959912 + 453 WP_096823570.1 hypothetical protein -
CLC90_RS13640 2959909..2960347 + 439 Protein_2627 hypothetical protein -
CLC90_RS13645 2960420..2960686 + 267 Protein_2628 DUF905 family protein -
CLC90_RS13650 2960759..2961580 + 822 WP_096823571.1 DUF945 domain-containing protein -
CLC90_RS13655 2961611..2962054 + 444 WP_096823572.1 antirestriction protein -
CLC90_RS13660 2962067..2962609 + 543 WP_096823573.1 DNA repair protein RadC -
CLC90_RS13665 2962606..2962827 + 222 WP_069325310.1 DUF987 domain-containing protein -
CLC90_RS13670 2962853..2963218 + 366 WP_096823574.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
CLC90_RS13675 2963257..2963586 + 330 WP_096823575.1 TA system toxin CbtA family protein Toxin
CLC90_RS13680 2963982..2964911 + 930 Protein_2635 integrase arm-type DNA-binding domain-containing protein -
CLC90_RS13685 2965157..2965711 + 555 WP_096823577.1 DUF4942 domain-containing protein -
CLC90_RS13690 2965820..2966143 + 324 WP_038277221.1 type II toxin-antitoxin system RelE/ParE family toxin -
CLC90_RS13695 2966130..2966411 + 282 WP_038277219.1 helix-turn-helix domain-containing protein -
CLC90_RS13700 2966620..2968160 - 1541 Protein_2639 IS3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2962853..2975954 13101
- flank IS/Tn - - 2968363..2968629 266


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-108)

Antitoxin

Antitoxin CbeA

(17-117)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 12376.18 Da        Isoelectric Point: 8.0799

>T80587 WP_096823575.1 NZ_CP023184:2963257-2963586 [Yersinia ruckeri]
MQTLSSHPTRASQPCLSPVEIWQLLLTHLLSQHYGLTLNDTPFINETTIREHIDAGVSLSDAVNFLVEKYGLVRIDRKGF
SWQEQTPYISVVDILRARRSTGLLKTNVK

Download         Length: 330 bp

>T80587 NZ_CP023184:2963257-2963586 [Yersinia ruckeri]
ATGCAAACCTTATCATCACACCCGACACGGGCGTCTCAGCCCTGCCTGTCACCCGTTGAAATCTGGCAGCTGCTGCTGAC
TCATTTGTTGTCGCAGCACTATGGCCTGACGCTGAATGACACACCGTTCATTAATGAAACCACCATCCGGGAACATATTG
ATGCTGGAGTATCGCTCAGCGATGCGGTGAACTTTCTGGTAGAAAAATATGGGCTTGTCCGTATCGACCGGAAGGGATTT
TCGTGGCAAGAACAGACCCCATATATTTCCGTAGTTGATATTCTGCGAGCAAGGCGCTCTACCGGCTTGCTAAAAACCAA
CGTGAAATAA

Antitoxin


Download         Length: 122 a.a.        Molecular weight: 13414.09 Da        Isoelectric Point: 5.4157

>AT80587 WP_096823574.1 NZ_CP023184:2962853-2963218 [Yersinia ruckeri]
MNNHSESVTKPENPACQQWGLKSTITPCFGARLVLEGNRLHFLADRAGFNGAFSDDDALHLDHAFPLILKQLELMLTSGE
LSPRHQHCVTLYHNGLTCEADTLGSCGYVYIAIYPDQTEPQ

Download         Length: 366 bp

>AT80587 NZ_CP023184:2962853-2963218 [Yersinia ruckeri]
ATGAACAATCACTCAGAATCCGTTACCAAGCCGGAGAATCCCGCCTGCCAGCAGTGGGGACTAAAGAGTACGATCACACC
CTGTTTTGGAGCTCGTCTGGTGCTGGAAGGCAACCGCTTGCATTTTCTCGCTGACCGGGCCGGATTCAACGGTGCTTTCA
GCGACGATGACGCGCTGCACCTAGATCATGCCTTTCCGTTGATACTCAAGCAACTGGAGCTGATGCTCACCAGCGGAGAA
CTCTCTCCCCGGCATCAGCACTGCGTCACGCTATATCACAACGGACTCACTTGCGAAGCCGACACACTCGGCTCCTGTGG
CTATGTCTACATTGCTATTTATCCTGACCAGACTGAGCCGCAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References