Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2242453..2242724 | Replicon | chromosome |
| Accession | NZ_CP023165 | ||
| Organism | Escherichia coli O22:H8 strain RM10809-3 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2242491..2242594 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2242453..2242724 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CLC88_RS11780 | 2239610..2241049 | + | 1440 | WP_000057022.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| CLC88_RS11785 | 2241167..2241403 | + | 237 | WP_001295499.1 | DUF1480 family protein | - |
| CLC88_RS11790 | 2241508..2241699 | + | 192 | WP_001296140.1 | YebW family protein | - |
| CLC88_RS11795 | 2241700..2242356 | - | 657 | WP_000812712.1 | protein-serine/threonine phosphatase | - |
| - | 2242453..2242724 | + | 272 | - | - | Antitoxin |
| - | 2242491..2242594 | - | 104 | - | - | Toxin |
| CLC88_RS11800 | 2242752..2243093 | - | 342 | WP_000976472.1 | YebY family protein | - |
| CLC88_RS11805 | 2243106..2243978 | - | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| CLC88_RS11810 | 2243982..2244356 | - | 375 | WP_000204700.1 | CopC domain-containing protein YobA | - |
| CLC88_RS11815 | 2244495..2244725 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| CLC88_RS11820 | 2244827..2245483 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein | - |
| CLC88_RS11825 | 2245507..2246169 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T80555 NZ_CP023165:c2242594-2242491 [Escherichia coli O22:H8]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 272 bp
>AT80555 NZ_CP023165:2242453-2242724 [Escherichia coli O22:H8]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
