Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4571292..4571653 Replicon chromosome
Accession NZ_CP023159
Organism Xanthomonas citri pv. malvacearum strain MS14003

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag CIW72_RS20585 Protein ID WP_005914328.1
Coordinates 4571292..4571426 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag CIW72_RS20590 Protein ID WP_003486606.1
Coordinates 4571501..4571653 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CIW72_RS20565 4566429..4568120 - 1692 WP_033481741.1 M20/M25/M40 family metallo-hydrolase -
CIW72_RS20570 4568312..4569346 - 1035 WP_050554793.1 MBL fold metallo-hydrolase -
CIW72_RS20575 4569385..4570674 - 1290 WP_005914329.1 tryptophan--tRNA ligase -
CIW72_RS20580 4570856..4571065 - 210 WP_003486601.1 CsbD family protein -
CIW72_RS20585 4571292..4571426 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
CIW72_RS20590 4571501..4571653 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
CIW72_RS20595 4571760..4572683 - 924 WP_005914327.1 arginase -
CIW72_RS20600 4573004..4573456 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
CIW72_RS20605 4573520..4573879 + 360 WP_005914325.1 hypothetical protein -
CIW72_RS20610 4573976..4574893 + 918 WP_033481739.1 hypothetical protein -
CIW72_RS20615 4574890..4575432 + 543 WP_003486615.1 GTPase -
CIW72_RS20625 4575914..4576597 + 684 WP_003486617.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T80537 WP_005914328.1 NZ_CP023159:c4571426-4571292 [Xanthomonas citri pv. malvacearum]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T80537 NZ_CP023159:c4571426-4571292 [Xanthomonas citri pv. malvacearum]
ATGAAGCGTGCAATTGTGCTGCTGGTGTTATCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT80537 WP_003486606.1 NZ_CP023159:c4571653-4571501 [Xanthomonas citri pv. malvacearum]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT80537 NZ_CP023159:c4571653-4571501 [Xanthomonas citri pv. malvacearum]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References