Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 100695..101239 Replicon chromosome
Accession NZ_CP023159
Organism Xanthomonas citri pv. malvacearum strain MS14003

Toxin (Protein)


Gene name relE Uniprot ID A0A7X9UUA0
Locus tag CIW72_RS00440 Protein ID WP_033479617.1
Coordinates 100940..101239 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A828YMS8
Locus tag CIW72_RS00435 Protein ID WP_005912560.1
Coordinates 100695..100952 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CIW72_RS00420 95827..97296 - 1470 WP_005912554.1 ribonuclease H-like domain-containing protein -
CIW72_RS00425 97293..99788 - 2496 WP_005912556.1 DEAD/DEAH box helicase -
CIW72_RS00430 99966..100628 + 663 WP_005912558.1 hemolysin III family protein -
CIW72_RS00435 100695..100952 + 258 WP_005912560.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CIW72_RS00440 100940..101239 + 300 WP_033479617.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CIW72_RS00450 101419..102318 - 900 WP_005912564.1 SDR family NAD(P)-dependent oxidoreductase -
CIW72_RS00455 102377..103114 - 738 WP_005912566.1 SDR family oxidoreductase -
CIW72_RS00460 103240..104151 + 912 WP_005912568.1 LysR family transcriptional regulator -
CIW72_RS00465 104350..105060 + 711 WP_005912570.1 hypothetical protein -
CIW72_RS00470 105251..105757 - 507 WP_005912572.1 NAD(P)H-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11246.00 Da        Isoelectric Point: 9.7235

>T80536 WP_033479617.1 NZ_CP023159:100940-101239 [Xanthomonas citri pv. malvacearum]
MAEIIWSVPALADLDAIADYIAIDNAPAAAALVKRVFAHVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VVVHVMRSERALRGNRLSR

Download         Length: 300 bp

>T80536 NZ_CP023159:100940-101239 [Xanthomonas citri pv. malvacearum]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATTGCCGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGCTGGTGAAACGGGTGTTCGCGCACGTTGAGCAATTGATCGAACACCCGGACAGCGGAAGCCGGCCAC
AGGAACTCAAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGCATC
GTGGTGGTGCACGTCATGCGGTCGGAGCGCGCGCTTCGCGGGAACCGTCTTTCACGCTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9646.15 Da        Isoelectric Point: 8.6223

>AT80536 WP_005912560.1 NZ_CP023159:100695-100952 [Xanthomonas citri pv. malvacearum]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVAEGRTLSHEQAQQRM
ARWLK

Download         Length: 258 bp

>AT80536 NZ_CP023159:100695-100952 [Xanthomonas citri pv. malvacearum]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACTCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGTGCCTATCTGGTGGATGTTGCCAGCTATGAGCGCATGCAGCAGCGCATTGCGC
TCCTCGAAGGAATCGCCCGTGGAGAAATGGCAGTTGCGGAAGGCCGTACGCTGAGCCATGAACAGGCACAGCAACGCATG
GCGCGATGGCTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7X9UUA0

Antitoxin

Source ID Structure
AlphaFold DB A0A828YMS8

References