Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 13216..13753 Replicon plasmid unnamed2
Accession NZ_CP023157
Organism Xanthomonas citri pv. malvacearum strain AR81009

Toxin (Protein)


Gene name relE Uniprot ID A0A7X9YU06
Locus tag CIW71_RS24455 Protein ID WP_017158383.1
Coordinates 13216..13497 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7X9UWY6
Locus tag CIW71_RS24460 Protein ID WP_017158384.1
Coordinates 13484..13753 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CIW71_RS24405 8443..8859 + 417 WP_017159868.1 hypothetical protein -
CIW71_RS24410 8996..9223 + 228 WP_039582726.1 antitoxin MazE family protein -
CIW71_RS24415 9210..9536 + 327 WP_007968778.1 type II toxin-antitoxin system PemK/MazF family toxin -
CIW71_RS24420 9582..10226 - 645 WP_039580900.1 Abi family protein -
CIW71_RS24435 10773..11168 - 396 WP_046830812.1 hypothetical protein -
CIW71_RS24440 11527..11973 + 447 WP_017160486.1 hypothetical protein -
CIW71_RS24445 11982..12677 + 696 WP_017154898.1 hypothetical protein -
CIW71_RS24450 12725..13078 + 354 WP_017161436.1 hypothetical protein -
CIW71_RS24455 13216..13497 - 282 WP_017158383.1 type II toxin-antitoxin system YafQ family toxin Toxin
CIW71_RS24460 13484..13753 - 270 WP_017158384.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
CIW71_RS24465 13862..14824 - 963 WP_007968792.1 recombinase family protein -
CIW71_RS24475 15376..15657 - 282 WP_017161425.1 hypothetical protein -
CIW71_RS24480 15681..16379 - 699 WP_078538983.1 AAA family ATPase -
CIW71_RS24485 17063..17881 - 819 WP_039582270.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..22827 22827


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-93)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(7-86)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10679.06 Da        Isoelectric Point: 8.9188

>T80535 WP_017158383.1 NZ_CP023157:c13497-13216 [Xanthomonas citri pv. malvacearum]
MRTIDRSSAFKRDYKREAKGQHRATLDDAIKPVLVALATDQPPDARYRDHDLSGDWAGYRECHIKPDLLLIYRKSDPDTL
RLARLGSHSELFG

Download         Length: 282 bp

>T80535 NZ_CP023157:c13497-13216 [Xanthomonas citri pv. malvacearum]
ATGCGGACGATTGACCGTTCATCCGCTTTCAAGCGCGACTACAAGCGGGAAGCCAAGGGGCAGCATCGCGCCACGCTTGA
TGACGCGATCAAGCCGGTGTTGGTCGCACTGGCGACCGATCAGCCTCCCGATGCACGCTATCGCGATCACGATCTTTCCG
GCGATTGGGCGGGCTATCGGGAATGTCACATCAAGCCCGACTTGCTGCTGATCTACCGCAAGTCCGACCCCGACACCCTG
CGACTGGCACGGCTTGGCTCGCACAGCGAGCTTTTCGGCTGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9719.10 Da        Isoelectric Point: 5.6976

>AT80535 WP_017158384.1 NZ_CP023157:c13753-13484 [Xanthomonas citri pv. malvacearum]
MSTTADTYVRARIDTATKERAASALEAMGLSISDAIRLLMLRIADEHRLPFDVKVPNTTTKKAIAELESGKGKKFANVDD
LMADLHADD

Download         Length: 270 bp

>AT80535 NZ_CP023157:c13753-13484 [Xanthomonas citri pv. malvacearum]
ATGAGCACTACCGCCGATACCTACGTCCGCGCCCGCATCGACACCGCCACCAAGGAACGTGCCGCTAGTGCGCTCGAAGC
AATGGGGCTGTCGATCTCTGATGCTATCCGCCTGCTGATGCTACGCATTGCCGACGAACACCGCCTGCCCTTCGATGTGA
AGGTACCAAACACCACCACGAAAAAGGCGATTGCCGAACTGGAATCAGGCAAGGGTAAGAAGTTCGCCAATGTGGACGAC
CTGATGGCGGATTTGCATGCGGACGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7X9YU06

Antitoxin

Source ID Structure
AlphaFold DB A0A7X9UWY6

References