80530

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 486791..487152 Replicon chromosome
Accession NZ_CP023155
Organism Xanthomonas citri pv. malvacearum strain AR81009

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag CIW71_RS02195 Protein ID WP_005914328.1
Coordinates 487018..487152 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag CIW71_RS02190 Protein ID WP_003486606.1
Coordinates 486791..486943 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CIW71_RS02155 481847..482530 - 684 WP_003486617.1 dTMP kinase -
CIW71_RS02165 483012..483554 - 543 WP_003486615.1 GTPase -
CIW71_RS02170 483551..484468 - 918 WP_033481739.1 hypothetical protein -
CIW71_RS02175 484565..484924 - 360 WP_003486613.1 hypothetical protein -
CIW71_RS02180 484988..485440 - 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
CIW71_RS02185 485761..486684 + 924 WP_005914327.1 arginase -
CIW71_RS02190 486791..486943 + 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
CIW71_RS02195 487018..487152 + 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
CIW71_RS02200 487379..487588 + 210 WP_003486601.1 CsbD family protein -
CIW71_RS02205 487770..489059 + 1290 WP_005914329.1 tryptophan--tRNA ligase -
CIW71_RS02210 489098..490132 + 1035 WP_050554793.1 MBL fold metallo-hydrolase -
CIW71_RS02215 490324..492015 + 1692 WP_033479687.1 M20/M25/M40 family metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T80530 WP_005914328.1 NZ_CP023155:487018-487152 [Xanthomonas citri pv. malvacearum]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T80530 NZ_CP023155:487018-487152 [Xanthomonas citri pv. malvacearum]
ATGAAGCGTGCAATTGTGCTGCTGGTGTTATCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT80530 WP_003486606.1 NZ_CP023155:486791-486943 [Xanthomonas citri pv. malvacearum]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT80530 NZ_CP023155:486791-486943 [Xanthomonas citri pv. malvacearum]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References