Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 225632..226169 Replicon chromosome
Accession NZ_CP023155
Organism Xanthomonas citri pv. malvacearum strain AR81009

Toxin (Protein)


Gene name relE Uniprot ID A0A7X9YU06
Locus tag CIW71_RS01010 Protein ID WP_017158383.1
Coordinates 225632..225913 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7X9UWY6
Locus tag CIW71_RS01015 Protein ID WP_017158384.1
Coordinates 225900..226169 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CIW71_RS00985 221438..223012 - 1575 WP_095702034.1 type IV secretion system DNA-binding domain-containing protein -
CIW71_RS25090 223016..223189 - 174 WP_164722239.1 hypothetical protein -
CIW71_RS00990 223189..223584 - 396 WP_039447651.1 hypothetical protein -
CIW71_RS00995 223943..224389 + 447 WP_017166397.1 hypothetical protein -
CIW71_RS01000 224398..225093 + 696 WP_017158799.1 hypothetical protein -
CIW71_RS01005 225141..225494 + 354 WP_017160495.1 hypothetical protein -
CIW71_RS01010 225632..225913 - 282 WP_017158383.1 type II toxin-antitoxin system YafQ family toxin Toxin
CIW71_RS01015 225900..226169 - 270 WP_017158384.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
CIW71_RS01020 226278..226748 - 471 WP_198303407.1 resolvase -
CIW71_RS01025 227439..228584 - 1146 WP_025990656.1 DUF4236 domain-containing protein -
CIW71_RS01030 228982..229353 - 372 Protein_195 recombinase family protein -
CIW71_RS01040 229905..230186 - 282 WP_017161425.1 hypothetical protein -
CIW71_RS01045 230210..230908 - 699 WP_078538983.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 206177..228925 22748


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-93)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(7-86)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10679.06 Da        Isoelectric Point: 8.9188

>T80529 WP_017158383.1 NZ_CP023155:c225913-225632 [Xanthomonas citri pv. malvacearum]
MRTIDRSSAFKRDYKREAKGQHRATLDDAIKPVLVALATDQPPDARYRDHDLSGDWAGYRECHIKPDLLLIYRKSDPDTL
RLARLGSHSELFG

Download         Length: 282 bp

>T80529 NZ_CP023155:c225913-225632 [Xanthomonas citri pv. malvacearum]
ATGCGGACGATTGACCGTTCATCCGCTTTCAAGCGCGACTACAAGCGGGAAGCCAAGGGGCAGCATCGCGCCACGCTTGA
TGACGCGATCAAGCCGGTGTTGGTCGCACTGGCGACCGATCAGCCTCCCGATGCACGCTATCGCGATCACGATCTTTCCG
GCGATTGGGCGGGCTATCGGGAATGTCACATCAAGCCCGACTTGCTGCTGATCTACCGCAAGTCCGACCCCGACACCCTG
CGACTGGCACGGCTTGGCTCGCACAGCGAGCTTTTCGGCTGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9719.10 Da        Isoelectric Point: 5.6976

>AT80529 WP_017158384.1 NZ_CP023155:c226169-225900 [Xanthomonas citri pv. malvacearum]
MSTTADTYVRARIDTATKERAASALEAMGLSISDAIRLLMLRIADEHRLPFDVKVPNTTTKKAIAELESGKGKKFANVDD
LMADLHADD

Download         Length: 270 bp

>AT80529 NZ_CP023155:c226169-225900 [Xanthomonas citri pv. malvacearum]
ATGAGCACTACCGCCGATACCTACGTCCGCGCCCGCATCGACACCGCCACCAAGGAACGTGCCGCTAGTGCGCTCGAAGC
AATGGGGCTGTCGATCTCTGATGCTATCCGCCTGCTGATGCTACGCATTGCCGACGAACACCGCCTGCCCTTCGATGTGA
AGGTACCAAACACCACCACGAAAAAGGCGATTGCCGAACTGGAATCAGGCAAGGGTAAGAAGTTCGCCAATGTGGACGAC
CTGATGGCGGATTTGCATGCGGACGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7X9YU06

Antitoxin

Source ID Structure
AlphaFold DB A0A7X9UWY6

References