Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 116388..116932 Replicon chromosome
Accession NZ_CP023155
Organism Xanthomonas citri pv. malvacearum strain AR81009

Toxin (Protein)


Gene name relE Uniprot ID A0A7X9UUA0
Locus tag CIW71_RS00520 Protein ID WP_033479617.1
Coordinates 116633..116932 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A828YMS8
Locus tag CIW71_RS00515 Protein ID WP_005912560.1
Coordinates 116388..116645 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CIW71_RS00500 111526..112989 - 1464 WP_005921792.1 ribonuclease H-like domain-containing protein -
CIW71_RS00505 112986..115481 - 2496 WP_165690593.1 DEAD/DEAH box helicase -
CIW71_RS00510 115659..116321 + 663 WP_005912558.1 hemolysin III family protein -
CIW71_RS00515 116388..116645 + 258 WP_005912560.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CIW71_RS00520 116633..116932 + 300 WP_033479617.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CIW71_RS00530 117112..118011 - 900 WP_033836121.1 SDR family NAD(P)-dependent oxidoreductase -
CIW71_RS00535 118070..118807 - 738 WP_005912566.1 SDR family oxidoreductase -
CIW71_RS00540 118933..119844 + 912 WP_005912568.1 LysR family transcriptional regulator -
CIW71_RS00545 120043..120270 + 228 Protein_102 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11246.00 Da        Isoelectric Point: 9.7235

>T80527 WP_033479617.1 NZ_CP023155:116633-116932 [Xanthomonas citri pv. malvacearum]
MAEIIWSVPALADLDAIADYIAIDNAPAAAALVKRVFAHVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VVVHVMRSERALRGNRLSR

Download         Length: 300 bp

>T80527 NZ_CP023155:116633-116932 [Xanthomonas citri pv. malvacearum]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATTGCCGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGCTGGTGAAACGGGTGTTCGCGCACGTTGAGCAATTGATCGAACACCCGGACAGCGGAAGCCGGCCAC
AGGAACTCAAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGCATC
GTGGTGGTGCACGTCATGCGGTCGGAGCGCGCGCTTCGCGGGAACCGTCTTTCACGCTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9646.15 Da        Isoelectric Point: 8.6223

>AT80527 WP_005912560.1 NZ_CP023155:116388-116645 [Xanthomonas citri pv. malvacearum]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVAEGRTLSHEQAQQRM
ARWLK

Download         Length: 258 bp

>AT80527 NZ_CP023155:116388-116645 [Xanthomonas citri pv. malvacearum]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACTCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGTGCCTATCTGGTGGATGTTGCCAGCTATGAGCGCATGCAGCAGCGCATTGCGC
TCCTCGAAGGAATCGCCCGTGGAGAAATGGCAGTTGCGGAAGGCCGTACGCTGAGCCATGAACAGGCACAGCAACGCATG
GCGCGATGGCTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7X9UUA0

Antitoxin

Source ID Structure
AlphaFold DB A0A828YMS8

References