Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 121347..122149 Replicon plasmid pSJ05684a
Accession NZ_CP023069
Organism Ensifer sojae CCBAU 05684

Toxin (Protein)


Gene name TacT3 Uniprot ID I3XHG7
Locus tag SJ05684_RS27770 Protein ID WP_014857792.1
Coordinates 121622..122149 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID A0A178YHY5
Locus tag SJ05684_RS27765 Protein ID WP_015633362.1
Coordinates 121347..121625 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SJ05684_RS27740 117662..118848 - 1187 Protein_111 IS3 family transposase -
SJ05684_RS27745 118846..119043 + 198 Protein_112 phasin family protein -
SJ05684_RS27750 119270..119982 + 713 Protein_113 IS6 family transposase -
SJ05684_RS27755 119966..120316 + 351 WP_100209425.1 hypothetical protein -
SJ05684_RS27760 120396..121253 + 858 WP_014857794.1 hypothetical protein -
SJ05684_RS27765 121347..121625 + 279 WP_015633362.1 DUF1778 domain-containing protein Antitoxin
SJ05684_RS27770 121622..122149 + 528 WP_014857792.1 hypothetical protein Toxin
SJ05684_RS27775 122273..124042 - 1770 Protein_118 hypothetical protein -
SJ05684_RS27780 124043..124450 - 408 Protein_119 threonine transporter -
SJ05684_RS27785 124438..125469 - 1032 WP_014857789.1 hypothetical protein -
SJ05684_RS27790 125548..126627 + 1080 WP_037446536.1 IS630 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Mobilizable plasmid - gmd 1..410255 410255


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(5-86)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 18735.62 Da        Isoelectric Point: 8.2948

>T80447 WP_014857792.1 NZ_CP023069:121622-122149 [Ensifer sojae CCBAU 05684]
MTLPAWHEEPIAKSHGRAVFDCGDGQMNEFLLRFARQSHEQNASKTFCAIDDAVPGRILGFYTIAPSAVEHATVPDAMTR
GLSRHDVPGFKLARLATDRAVAGQGLGGRLLAAAALRCLRLAGEGGGLLLIIDAKGERAANWYASYGAEPLKDKPLTLVM
PLITFAADLRARGLL

Download         Length: 528 bp

>T80447 NZ_CP023069:121622-122149 [Ensifer sojae CCBAU 05684]
ATGACTTTACCTGCATGGCATGAGGAACCGATCGCTAAGTCTCACGGTCGGGCAGTTTTCGATTGCGGCGACGGTCAGAT
GAACGAGTTTTTGCTCCGCTTTGCTCGACAGAGCCATGAGCAGAATGCCTCGAAAACCTTCTGTGCTATCGACGACGCAG
TGCCCGGCCGTATTCTTGGGTTCTATACGATCGCGCCCTCGGCAGTCGAGCATGCGACTGTGCCAGATGCAATGACACGC
GGTCTTTCCCGCCATGACGTGCCAGGCTTCAAGCTCGCGCGATTGGCTACCGACCGCGCGGTTGCCGGGCAGGGACTGGG
AGGCCGGCTCCTAGCCGCCGCCGCGCTCCGCTGCCTGCGACTTGCAGGAGAGGGCGGGGGACTTTTACTGATCATCGATG
CCAAAGGCGAGCGAGCCGCCAACTGGTACGCTTCCTATGGTGCCGAACCGCTAAAGGACAAGCCGCTAACTCTCGTAATG
CCGCTCATCACCTTCGCGGCCGACTTGCGTGCTAGAGGTCTCCTTTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 9999.57 Da        Isoelectric Point: 10.0863

>AT80447 WP_015633362.1 NZ_CP023069:121347-121625 [Ensifer sojae CCBAU 05684]
MPSIANENSERMSLRVPATAKAKLVRAAALRNTDLTDFVTQSALREAEAVIEEAETIKVSKRDHLRILELLENPPKPNAK
LRAAIAGLPGSL

Download         Length: 279 bp

>AT80447 NZ_CP023069:121347-121625 [Ensifer sojae CCBAU 05684]
ATGCCGAGCATAGCGAACGAGAACAGCGAACGTATGAGTTTGAGGGTGCCTGCCACGGCCAAGGCTAAACTCGTACGCGC
TGCGGCACTTCGTAATACCGATCTGACGGATTTCGTGACGCAATCCGCGCTGCGAGAAGCAGAGGCTGTGATCGAGGAAG
CCGAGACGATCAAAGTGTCGAAGCGCGATCATCTTCGCATTCTTGAGCTTCTGGAAAATCCGCCTAAACCTAACGCCAAG
CTGCGCGCGGCGATTGCCGGTTTGCCTGGCAGCCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB I3XHG7

Antitoxin

Source ID Structure
AlphaFold DB A0A178YHY5

References