Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /RES-Xre |
| Location | 1072767..1073704 | Replicon | plasmid pSS05631b |
| Accession | NZ_CP023064 | ||
| Organism | Sinorhizobium sp. CCBAU 05631 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | A0A2S3YRR4 |
| Locus tag | SS05631_RS24445 | Protein ID | WP_037416676.1 |
| Coordinates | 1072767..1073330 (-) | Length | 188 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | A0A1L3LF60 |
| Locus tag | SS05631_RS24450 | Protein ID | WP_037384278.1 |
| Coordinates | 1073333..1073704 (-) | Length | 124 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SS05631_RS24425 | 1068409..1069266 | + | 858 | WP_037416688.1 | sulfate ABC transporter permease subunit CysT | - |
| SS05631_RS24430 | 1069256..1070140 | + | 885 | WP_037416685.1 | sulfate ABC transporter permease subunit CysW | - |
| SS05631_RS24435 | 1070156..1071265 | + | 1110 | WP_037416682.1 | sulfate/molybdate ABC transporter ATP-binding protein | - |
| SS05631_RS24440 | 1071409..1072770 | + | 1362 | WP_037416679.1 | FAD-binding oxidoreductase | - |
| SS05631_RS24445 | 1072767..1073330 | - | 564 | WP_037416676.1 | RES domain-containing protein | Toxin |
| SS05631_RS24450 | 1073333..1073704 | - | 372 | WP_037384278.1 | DUF2384 domain-containing protein | Antitoxin |
| SS05631_RS24455 | 1073880..1074665 | - | 786 | WP_037416673.1 | crotonase/enoyl-CoA hydratase family protein | - |
| SS05631_RS24460 | 1074662..1075531 | - | 870 | WP_037416670.1 | hydroxymethylglutaryl-CoA lyase | - |
| SS05631_RS24465 | 1075528..1077516 | - | 1989 | WP_037416667.1 | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | - |
| SS05631_RS24470 | 1077532..1077915 | - | 384 | WP_037416664.1 | RidA family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | katA | 1..1501701 | 1501701 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 188 a.a. Molecular weight: 20877.66 Da Isoelectric Point: 7.9236
>T80440 WP_037416676.1 NZ_CP023064:c1073330-1072767 [Sinorhizobium sp. CCBAU 05631]
MRRSVSGSPPASRSDQEQMSPAEPMTLWRAFVPRWAHMPLSGEGAARFGGRWNPVGTPTIYAARELSTAWAEYNQGFVQH
PALIVQLELRDAKLADLTSGDVLAELRLEEAIHRCEWRDALDRGSMPHTHKTRADLLKRGYDGVIYPSYMSPGGTCVALW
RWNGRSGPQLDVIDPEGRLPKSPASWL
MRRSVSGSPPASRSDQEQMSPAEPMTLWRAFVPRWAHMPLSGEGAARFGGRWNPVGTPTIYAARELSTAWAEYNQGFVQH
PALIVQLELRDAKLADLTSGDVLAELRLEEAIHRCEWRDALDRGSMPHTHKTRADLLKRGYDGVIYPSYMSPGGTCVALW
RWNGRSGPQLDVIDPEGRLPKSPASWL
Download Length: 564 bp
>T80440 NZ_CP023064:c1073330-1072767 [Sinorhizobium sp. CCBAU 05631]
ATGAGGAGAAGTGTGAGCGGATCTCCGCCCGCGTCCCGCTCCGATCAGGAACAAATGTCGCCGGCGGAGCCGATGACGCT
CTGGCGTGCCTTCGTGCCCCGCTGGGCGCATATGCCGCTTTCCGGAGAGGGTGCCGCCCGGTTCGGTGGCCGATGGAATC
CCGTCGGCACGCCGACGATCTACGCGGCGCGGGAGCTTTCCACCGCTTGGGCCGAATATAACCAGGGTTTCGTGCAGCAT
CCGGCGCTGATCGTCCAACTCGAGCTTCGCGACGCGAAGCTGGCGGACCTGACGAGTGGCGATGTGCTTGCCGAACTCCG
GCTGGAAGAGGCGATCCACCGCTGCGAATGGCGCGACGCACTCGACAGGGGCTCAATGCCGCATACGCACAAGACCCGGG
CCGACCTTCTGAAGCGCGGCTATGACGGCGTGATCTATCCGTCCTACATGTCGCCCGGCGGCACATGTGTCGCCCTCTGG
CGCTGGAACGGCCGGAGCGGACCGCAGCTCGACGTCATCGATCCAGAGGGCCGGCTCCCGAAATCGCCAGCCTCCTGGCT
TTAG
ATGAGGAGAAGTGTGAGCGGATCTCCGCCCGCGTCCCGCTCCGATCAGGAACAAATGTCGCCGGCGGAGCCGATGACGCT
CTGGCGTGCCTTCGTGCCCCGCTGGGCGCATATGCCGCTTTCCGGAGAGGGTGCCGCCCGGTTCGGTGGCCGATGGAATC
CCGTCGGCACGCCGACGATCTACGCGGCGCGGGAGCTTTCCACCGCTTGGGCCGAATATAACCAGGGTTTCGTGCAGCAT
CCGGCGCTGATCGTCCAACTCGAGCTTCGCGACGCGAAGCTGGCGGACCTGACGAGTGGCGATGTGCTTGCCGAACTCCG
GCTGGAAGAGGCGATCCACCGCTGCGAATGGCGCGACGCACTCGACAGGGGCTCAATGCCGCATACGCACAAGACCCGGG
CCGACCTTCTGAAGCGCGGCTATGACGGCGTGATCTATCCGTCCTACATGTCGCCCGGCGGCACATGTGTCGCCCTCTGG
CGCTGGAACGGCCGGAGCGGACCGCAGCTCGACGTCATCGATCCAGAGGGCCGGCTCCCGAAATCGCCAGCCTCCTGGCT
TTAG
Antitoxin
Download Length: 124 a.a. Molecular weight: 13143.29 Da Isoelectric Point: 9.7796
>AT80440 WP_037384278.1 NZ_CP023064:c1073704-1073333 [Sinorhizobium sp. CCBAU 05631]
MMAVDFQIPAARFGDDHSPYLSARLVADRLGVTLAELAKLIGVARNTLTAKSGARKVDSALSKVVRILAMASEMAGDEAR
AVIWFKHQPIPGWAGKTAYDLVGEGKADKVLAYLEAIRAGVYA
MMAVDFQIPAARFGDDHSPYLSARLVADRLGVTLAELAKLIGVARNTLTAKSGARKVDSALSKVVRILAMASEMAGDEAR
AVIWFKHQPIPGWAGKTAYDLVGEGKADKVLAYLEAIRAGVYA
Download Length: 372 bp
>AT80440 NZ_CP023064:c1073704-1073333 [Sinorhizobium sp. CCBAU 05631]
ATGATGGCTGTCGACTTCCAGATTCCGGCGGCACGCTTCGGGGATGATCATTCGCCGTACCTGTCGGCACGCCTCGTCGC
CGACCGGCTCGGCGTCACACTTGCCGAACTCGCCAAGCTGATCGGCGTGGCACGCAACACGCTGACGGCAAAGTCTGGCG
CGCGAAAGGTCGACAGCGCTTTGAGCAAGGTCGTCCGCATCCTCGCAATGGCGTCTGAAATGGCCGGCGACGAAGCCCGC
GCCGTCATTTGGTTCAAACATCAGCCGATCCCCGGCTGGGCCGGCAAGACCGCCTATGACCTGGTCGGCGAAGGCAAGGC
CGACAAGGTCCTCGCCTATCTCGAGGCCATCCGCGCCGGCGTCTACGCCTGA
ATGATGGCTGTCGACTTCCAGATTCCGGCGGCACGCTTCGGGGATGATCATTCGCCGTACCTGTCGGCACGCCTCGTCGC
CGACCGGCTCGGCGTCACACTTGCCGAACTCGCCAAGCTGATCGGCGTGGCACGCAACACGCTGACGGCAAAGTCTGGCG
CGCGAAAGGTCGACAGCGCTTTGAGCAAGGTCGTCCGCATCCTCGCAATGGCGTCTGAAATGGCCGGCGACGAAGCCCGC
GCCGTCATTTGGTTCAAACATCAGCCGATCCCCGGCTGGGCCGGCAAGACCGCCTATGACCTGGTCGGCGAAGGCAAGGC
CGACAAGGTCCTCGCCTATCTCGAGGCCATCCGCGCCGGCGTCTACGCCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A2S3YRR4 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A1L3LF60 |