Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2193655..2193926 Replicon chromosome
Accession NZ_CP023061
Organism Escherichia coli strain FORC_069

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2193785..2193888 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2193655..2193926 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FORC69_RS11415 2190210..2190872 - 663 WP_000944256.1 exodeoxyribonuclease X -
FORC69_RS11420 2190896..2191552 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
FORC69_RS11425 2191654..2191884 - 231 WP_000916763.1 DNA polymerase III subunit theta -
FORC69_RS11430 2192023..2192397 + 375 WP_000204699.1 CopC domain-containing protein YobA -
FORC69_RS11435 2192401..2193273 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
FORC69_RS11440 2193286..2193627 + 342 WP_088888690.1 YebY family protein -
- 2193655..2193926 - 272 - - Antitoxin
- 2193785..2193888 + 104 - - Toxin
FORC69_RS11445 2194023..2194679 + 657 WP_000812712.1 protein-serine/threonine phosphatase -
FORC69_RS11450 2194680..2194871 - 192 WP_001296140.1 YebW family protein -
FORC69_RS11455 2194976..2195212 - 237 WP_001295499.1 DUF1480 family protein -
FORC69_RS11460 2195330..2196769 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2115920..2209765 93845


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T80416 NZ_CP023061:2193785-2193888 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT80416 NZ_CP023061:c2193926-2193655 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References