Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /GNAT-DUF1778
Location 1094299..1095060 Replicon chromosome
Accession NZ_CP023057
Organism Glaesserella sp. 15-184

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag CJD39_RS05010 Protein ID WP_111750486.1
Coordinates 1094299..1094790 (-) Length 164 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag CJD39_RS05015 Protein ID WP_111750485.1
Coordinates 1094794..1095060 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CJD39_RS04980 1090282..1091304 + 1023 WP_111750492.1 branched-chain amino acid aminotransferase -
CJD39_RS04985 1091387..1091731 + 345 WP_111750491.1 RidA family protein -
CJD39_RS04990 1091757..1092335 - 579 WP_111750490.1 crossover junction endodeoxyribonuclease RuvC -
CJD39_RS04995 1092409..1092930 - 522 WP_111750489.1 Holliday junction resolvase -
CJD39_RS05000 1092952..1093692 - 741 WP_111750488.1 YebC/PmpR family DNA-binding transcriptional regulator -
CJD39_RS05005 1093847..1094284 - 438 WP_111750487.1 dihydroneopterin triphosphate diphosphatase -
CJD39_RS05010 1094299..1094790 - 492 WP_111750486.1 GNAT family N-acetyltransferase Toxin
CJD39_RS05015 1094794..1095060 - 267 WP_111750485.1 DUF1778 domain-containing protein Antitoxin
CJD39_RS05020 1095153..1096922 - 1770 WP_111750484.1 aspartate--tRNA ligase -
CJD39_RS05025 1097103..1097699 + 597 WP_111750483.1 nucleotide exchange factor GrpE -
CJD39_RS05030 1097795..1098097 + 303 WP_111750482.1 hypothetical protein -
CJD39_RS05035 1098168..1098620 + 453 WP_111750481.1 DUF441 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(80-143)

Antitoxin

Vibrio phage ICP1, Orf50

(8-83)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 18684.90 Da        Isoelectric Point: 9.8558

>T80408 WP_111750486.1 NZ_CP023057:c1094790-1094299 [Glaesserella sp. 15-184]
MDIQLLDPSIHHRKYFDCGNPILNRFLQQTANQQAMKDTARTYVLVEPQQPTIILGFYTLTMTRLDVAELPEMLQKQAKF
PLSAGLLARLAVDKKHQQKGYAKILLRDALKNLYQASRIVGFPIIVVDAKDGVADFYQKYGFMPIQQSPNRLYLMARTLE
TLL

Download         Length: 492 bp

>T80408 NZ_CP023057:c1094790-1094299 [Glaesserella sp. 15-184]
ATGGATATTCAGTTATTAGATCCCAGCATTCATCATCGCAAATATTTTGACTGTGGTAACCCGATCTTAAATCGCTTTCT
GCAGCAGACAGCAAATCAGCAAGCGATGAAAGACACGGCACGCACTTATGTGTTGGTCGAACCGCAGCAGCCGACGATAA
TTTTAGGATTTTATACCTTAACAATGACACGGCTTGATGTGGCAGAATTACCTGAAATGTTACAAAAACAGGCAAAATTT
CCACTTTCGGCAGGCTTATTGGCTCGTTTGGCGGTGGATAAAAAGCATCAACAGAAAGGCTATGCGAAAATCCTGTTGCG
TGATGCGTTGAAAAATCTCTATCAAGCAAGTCGTATTGTTGGTTTCCCAATTATTGTGGTTGATGCAAAAGACGGCGTGG
CGGATTTTTATCAAAAGTATGGTTTTATGCCCATTCAGCAAAGTCCAAATCGCTTATATTTAATGGCTAGAACCCTAGAA
ACATTGTTATAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9872.25 Da        Isoelectric Point: 4.7318

>AT80408 WP_111750485.1 NZ_CP023057:c1095060-1094794 [Glaesserella sp. 15-184]
MTQASLPRITARIDVATQELLLNAAALVGISSLNSFVLNAAIEKANAILREEKMTQFNDEDTRLLLHYLDNPPEPNAHLR
SLFLDEQR

Download         Length: 267 bp

>AT80408 NZ_CP023057:c1095060-1094794 [Glaesserella sp. 15-184]
ATGACACAAGCAAGTTTACCCCGAATTACCGCTCGAATTGATGTGGCAACCCAAGAATTACTGCTTAATGCGGCAGCGTT
AGTGGGTATTTCTAGCCTAAATTCGTTTGTGCTAAACGCTGCGATTGAAAAGGCAAATGCAATTTTGCGTGAAGAAAAAA
TGACGCAGTTTAATGATGAAGATACCCGTTTGCTGCTGCACTATTTGGATAATCCACCTGAACCCAATGCCCATTTGCGA
TCGCTTTTTTTAGATGAGCAAAGATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References