Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 559869..560414 Replicon chromosome
Accession NZ_CP023057
Organism Glaesserella sp. 15-184

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CJD39_RS02565 Protein ID WP_111749144.1
Coordinates 560127..560414 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CJD39_RS02560 Protein ID WP_111749143.1
Coordinates 559869..560117 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CJD39_RS02545 555775..556704 + 930 WP_111749140.1 lipoprotein NlpI -
CJD39_RS02550 556973..558814 + 1842 WP_111749141.1 DEAD/DEAH box helicase -
CJD39_RS02555 559065..559577 + 513 WP_111749142.1 tRNA adenosine(34) deaminase TadA -
CJD39_RS02560 559869..560117 + 249 WP_111749143.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
CJD39_RS02565 560127..560414 + 288 WP_111749144.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CJD39_RS02570 560436..560951 - 516 WP_111749145.1 primosomal replication protein -
CJD39_RS02575 561417..562454 + 1038 WP_111749146.1 porin -
CJD39_RS02580 562657..563361 - 705 WP_111749147.1 carbonate dehydratase -
CJD39_RS02585 563490..563699 - 210 WP_111749148.1 cold shock domain-containing protein CspD -
CJD39_RS02590 563809..564378 - 570 WP_111749149.1 DUF1439 domain-containing protein -
CJD39_RS02595 564683..565321 + 639 WP_111749150.1 outer membrane lipoprotein chaperone LolA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type II bacterial toxin-antitoxin system, ParE-like toxin

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-71)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11215.07 Da        Isoelectric Point: 9.8072

>T80406 WP_111749144.1 NZ_CP023057:560127-560414 [Glaesserella sp. 15-184]
MTYSIKVHDDFIEELKKLDPAVKQQLRNKLNKIVENPHIPKNRLSGNLYNCYKIKLRKAGIRLIYQVNDDEIYILLLTVG
KRENNEVYDTALTRI

Download         Length: 288 bp

>T80406 NZ_CP023057:560127-560414 [Glaesserella sp. 15-184]
ATGACCTACTCTATTAAGGTCCATGATGATTTTATCGAAGAGTTAAAGAAACTTGATCCTGCCGTTAAACAACAATTGCG
TAATAAGCTCAATAAGATAGTAGAAAATCCACATATTCCGAAAAATCGGCTTAGTGGTAATTTATACAATTGCTATAAAA
TTAAACTCAGGAAGGCAGGCATACGTTTAATTTATCAAGTCAATGATGATGAGATTTATATTCTACTTTTAACGGTAGGT
AAACGAGAGAATAACGAAGTTTATGACACAGCACTTACTCGTATTTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9315.66 Da        Isoelectric Point: 4.3719

>AT80406 WP_111749143.1 NZ_CP023057:559869-560117 [Glaesserella sp. 15-184]
MANLNIRIDDEIKQQAFVVFDNLGVTPSDAIRAFLTYVANTGKMPLKQIIVSDEDAQLYELVQKRLNEPEKIKSTTLDEL
FS

Download         Length: 249 bp

>AT80406 NZ_CP023057:559869-560117 [Glaesserella sp. 15-184]
ATGGCAAACTTAAACATTCGTATTGATGATGAAATTAAACAACAGGCTTTTGTTGTTTTTGATAATTTAGGAGTAACGCC
TTCAGATGCTATTCGAGCTTTTTTGACTTATGTAGCAAATACAGGAAAAATGCCACTTAAGCAAATTATTGTTTCTGATG
AAGATGCGCAACTCTATGAATTAGTTCAAAAGCGTCTTAATGAACCTGAAAAAATCAAATCGACTACTTTAGATGAACTT
TTTTCATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References