Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /DUF1778(antitoxin) |
| Location | 625150..626102 | Replicon | chromosome |
| Accession | NZ_CP023055 | ||
| Organism | Vibrio anguillarum strain VIB43 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | A0A7U5NDE7 |
| Locus tag | CK207_RS18330 | Protein ID | WP_069211914.1 |
| Coordinates | 625150..625683 (-) | Length | 178 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | CK207_RS20950 | Protein ID | WP_164732805.1 |
| Coordinates | 625680..626102 (-) | Length | 141 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CK207_RS18295 | 620767..621138 | + | 372 | WP_013867787.1 | DUF3319 domain-containing protein | - |
| CK207_RS18300 | 621146..621457 | + | 312 | WP_019282715.1 | stress response translation initiation inhibitor YciH | - |
| CK207_RS18305 | 621727..622011 | - | 285 | WP_069212144.1 | hypothetical protein | - |
| CK207_RS18310 | 622008..622217 | - | 210 | WP_194568891.1 | hypothetical protein | - |
| CK207_RS18320 | 623556..623966 | + | 411 | Protein_594 | IS30 family transposase | - |
| CK207_RS18325 | 624024..624944 | - | 921 | WP_069211915.1 | hypothetical protein | - |
| CK207_RS18330 | 625150..625683 | - | 534 | WP_069211914.1 | GNAT family N-acetyltransferase | Toxin |
| CK207_RS20950 | 625680..626102 | - | 423 | WP_164732805.1 | DUF1778 domain-containing protein | Antitoxin |
| CK207_RS18345 | 626454..626647 | - | 194 | Protein_598 | IS4 family transposase | - |
| CK207_RS18350 | 626708..627783 | + | 1076 | Protein_599 | IS3 family transposase | - |
| CK207_RS18355 | 627857..629034 | + | 1178 | WP_095661382.1 | IS3 family transposase | - |
| CK207_RS18365 | 629297..629737 | - | 441 | WP_029190018.1 | hypothetical protein | - |
| CK207_RS18370 | 629903..630310 | - | 408 | WP_081245499.1 | ASCH domain-containing protein | - |
| CK207_RS20825 | 630954..631073 | - | 120 | Protein_603 | DUF3265 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 619705..629034 | 9329 | |
| - | inside | IScluster/Tn | - | - | 622341..647960 | 25619 | |
| - | inside | Integron | - | - | 624024..644923 | 20899 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 178 a.a. Molecular weight: 20293.67 Da Isoelectric Point: 9.3517
>T80404 WP_069211914.1 NZ_CP023055:c625683-625150 [Vibrio anguillarum]
VSWGKEFVELSKSKHDRDSFDCGEQELNTFIKTQAAKRMQAGISRTMVLPSAQPLLNQKFAICVFYSVAPSSISRETLPA
QLAKKLPRYPIPVFLLAQLAVHKEYHGSGLGKISLIRALKYLWEVNHHMRVYAIVVDCLTDSAQAFYTKFGFEVLCEYNE
RIRMFLPMKTVEQLFNQ
VSWGKEFVELSKSKHDRDSFDCGEQELNTFIKTQAAKRMQAGISRTMVLPSAQPLLNQKFAICVFYSVAPSSISRETLPA
QLAKKLPRYPIPVFLLAQLAVHKEYHGSGLGKISLIRALKYLWEVNHHMRVYAIVVDCLTDSAQAFYTKFGFEVLCEYNE
RIRMFLPMKTVEQLFNQ
Download Length: 534 bp
>T80404 NZ_CP023055:c625683-625150 [Vibrio anguillarum]
GTGAGTTGGGGTAAAGAGTTTGTAGAACTTAGTAAGTCAAAGCATGACCGCGATTCATTTGACTGTGGAGAGCAAGAGCT
AAACACATTTATCAAAACTCAAGCTGCAAAGCGCATGCAAGCAGGTATTAGCCGAACAATGGTTTTACCTAGTGCTCAAC
CACTGTTAAATCAAAAATTCGCTATTTGTGTATTTTATAGTGTTGCACCGAGTTCAATCAGTCGAGAAACATTGCCGGCA
CAACTAGCAAAGAAACTTCCTAGGTATCCAATCCCTGTTTTTCTTTTGGCTCAATTAGCTGTGCACAAAGAGTATCATGG
CTCTGGGCTCGGAAAAATTAGTCTAATTCGCGCACTGAAGTACTTATGGGAAGTGAATCATCACATGAGGGTATACGCAA
TAGTTGTGGACTGTCTGACAGATTCCGCTCAAGCGTTCTATACGAAGTTTGGCTTTGAAGTATTGTGCGAATATAATGAG
CGTATTCGTATGTTCTTACCAATGAAAACGGTAGAACAGCTTTTTAATCAATAG
GTGAGTTGGGGTAAAGAGTTTGTAGAACTTAGTAAGTCAAAGCATGACCGCGATTCATTTGACTGTGGAGAGCAAGAGCT
AAACACATTTATCAAAACTCAAGCTGCAAAGCGCATGCAAGCAGGTATTAGCCGAACAATGGTTTTACCTAGTGCTCAAC
CACTGTTAAATCAAAAATTCGCTATTTGTGTATTTTATAGTGTTGCACCGAGTTCAATCAGTCGAGAAACATTGCCGGCA
CAACTAGCAAAGAAACTTCCTAGGTATCCAATCCCTGTTTTTCTTTTGGCTCAATTAGCTGTGCACAAAGAGTATCATGG
CTCTGGGCTCGGAAAAATTAGTCTAATTCGCGCACTGAAGTACTTATGGGAAGTGAATCATCACATGAGGGTATACGCAA
TAGTTGTGGACTGTCTGACAGATTCCGCTCAAGCGTTCTATACGAAGTTTGGCTTTGAAGTATTGTGCGAATATAATGAG
CGTATTCGTATGTTCTTACCAATGAAAACGGTAGAACAGCTTTTTAATCAATAG
Antitoxin
Download Length: 141 a.a. Molecular weight: 15816.26 Da Isoelectric Point: 6.4738
>AT80404 WP_164732805.1 NZ_CP023055:c626102-625680 [Vibrio anguillarum]
VYFLSSAVRWQPLSRALYSLSFRKFSVLIEYALSLHYNQSAYGTYPYIGGVMATARLDIRLDEEIKAKAEKASALLGLKS
LTEYVVRLMDEDATHVIEEYESIMVKDSVFDEFMAACNKVKAPNQALLEAVKFTEKSGIK
VYFLSSAVRWQPLSRALYSLSFRKFSVLIEYALSLHYNQSAYGTYPYIGGVMATARLDIRLDEEIKAKAEKASALLGLKS
LTEYVVRLMDEDATHVIEEYESIMVKDSVFDEFMAACNKVKAPNQALLEAVKFTEKSGIK
Download Length: 423 bp
>AT80404 NZ_CP023055:c626102-625680 [Vibrio anguillarum]
GTGTATTTTTTGAGTTCGGCGGTGCGTTGGCAACCCCTTAGCCGGGCGTTATACTCTCTCTCGTTCCGTAAATTTTCTGT
ACTAATTGAATATGCCTTAAGTTTGCACTATAATCAATCAGCTTACGGAACATATCCGTACATTGGAGGGGTTATGGCAA
CGGCACGTTTAGATATCCGCCTTGATGAAGAGATCAAGGCAAAAGCCGAAAAAGCATCGGCTTTACTTGGTTTAAAAAGT
CTCACTGAATATGTAGTGAGACTTATGGACGAAGATGCGACTCATGTTATTGAGGAGTATGAAAGTATTATGGTTAAAGA
CAGTGTTTTTGACGAATTTATGGCTGCGTGTAATAAAGTAAAAGCACCGAATCAAGCTTTGCTTGAAGCTGTTAAATTTA
CAGAGAAGAGTGGTATCAAGTGA
GTGTATTTTTTGAGTTCGGCGGTGCGTTGGCAACCCCTTAGCCGGGCGTTATACTCTCTCTCGTTCCGTAAATTTTCTGT
ACTAATTGAATATGCCTTAAGTTTGCACTATAATCAATCAGCTTACGGAACATATCCGTACATTGGAGGGGTTATGGCAA
CGGCACGTTTAGATATCCGCCTTGATGAAGAGATCAAGGCAAAAGCCGAAAAAGCATCGGCTTTACTTGGTTTAAAAAGT
CTCACTGAATATGTAGTGAGACTTATGGACGAAGATGCGACTCATGTTATTGAGGAGTATGAAAGTATTATGGTTAAAGA
CAGTGTTTTTGACGAATTTATGGCTGCGTGTAATAAAGTAAAAGCACCGAATCAAGCTTTGCTTGAAGCTGTTAAATTTA
CAGAGAAGAGTGGTATCAAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|