Detailed information of TA system TA080336

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PanAT/DUF4065(antitoxin)
• Location: 3276043..3277016
• Replicon: chromosome
• Accession: NZ_CP023019
• Organism: Shewanella sp. WE21

Toxin (Protein)

• Gene name: panT
• Uniprot ID: -
• Locus tag: CKQ84_RS14335
• Protein ID: WP_105251796.1
• Coordinates: 3276043..3276456 (-)
• Length: 138 a.a.

Antitoxin (Protein)

• Gene name: panA
• Uniprot ID: -
• Locus tag: CKQ84_RS14340
• Protein ID: WP_105251797.1
• Coordinates: 3276453..3277016 (-)
• Length: 188 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CKQ84_RS14325	3272628..3273287	-	660	WP_105251794.1	hypothetical protein	-
CKQ84_RS14330	3273605..3274561	+	957	WP_105251795.1	IS110 family transposase	-
CKQ84_RS14335	3276043..3276456	-	414	WP_105251796.1	hypothetical protein	Toxin
CKQ84_RS14340	3276453..3277016	-	564	WP_105251797.1	SocA family protein	Antitoxin
CKQ84_RS14345	3277245..3277481	-	237	WP_105251798.1	hypothetical protein	-
CKQ84_RS14350	3277478..3279754	-	2277	WP_105251799.1	replication endonuclease	-
CKQ84_RS14360	3280062..3280661	-	600	WP_105251801.1	3'-5' exonuclease	-
CKQ84_RS14365	3280658..3280915	-	258	WP_105251802.1	hypothetical protein	-
CKQ84_RS14370	3280930..3281286	-	357	WP_105251803.1	hypothetical protein	-
CKQ84_RS23775	3281333..3281506	-	174	WP_158683062.1	hypothetical protein	-
CKQ84_RS14375	3281552..3281824	-	273	WP_105251804.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	3247952..3297220	49268
	-	flank	IS/Tn	-	-	3273605..3274561	956

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Antitoxin SocA-like, Panacea domain (29-141)

Sequences

Toxin

Protein

• Length: 138 a.a.
• Molecular weight: 15384.46 Da
• Isoelectric Point: 6.5943

>T80336 WP_105251796.1 NZ_CP023019:c3276456-3276043 [Shewanella sp. WE21]
VTQSHPYRKGSLLIPSGSCNHLHVICNDPVIYPSIGGYAVLAVNITSITPVIPHDQSCILKAGDHEFVKHDSYVYYRKAD
IFSAEKIVNALNDGSFIIHADFDEDTFGKILNGFEVSTEVSYKNKRFYEKYCKVLPE

Nucleotide

• Length: 414 bp

>T80336 NZ_CP023019:c3276456-3276043 [Shewanella sp. WE21]
GTGACGCAGAGCCATCCTTACCGAAAAGGGAGCCTTTTAATCCCTTCTGGCAGTTGTAATCATTTACACGTTATATGCAA
TGATCCGGTTATATACCCCAGCATAGGTGGTTACGCCGTGTTAGCAGTAAACATCACATCAATAACCCCCGTTATACCAC
ATGACCAATCTTGTATACTGAAAGCGGGTGATCATGAATTCGTAAAACATGACAGCTATGTGTATTACCGTAAAGCAGAC
ATTTTTAGCGCCGAAAAGATTGTCAATGCCTTAAATGATGGATCTTTTATTATTCACGCTGACTTTGATGAAGATACATT
TGGTAAAATTCTCAATGGATTTGAAGTAAGCACAGAAGTTTCATATAAGAATAAACGCTTTTATGAGAAATACTGCAAAG
TTTTGCCTGAATAA

Antitoxin

Protein

• Length: 188 a.a.
• Molecular weight: 21132.08 Da
• Isoelectric Point: 5.0422

>AT80336 WP_105251797.1 NZ_CP023019:c3277016-3276453 [Shewanella sp. WE21]
MIMFSEIKVAQMSAFILHLNGQKMSYLKLIKILYLAEREAVSRWGDSMSGDNFVSMPHGPVLSLTYNLITGGSRMESDGW
NKFISGCANYEVSSNLTNPDRDDWDELSDAELAIIESIFNKFKHLTRWELVDYTHDNCKEWIDPKGSSAPISLEKIIYAT
CDKSKTAALISFSKSMNELSDARSIIQ

Nucleotide

• Length: 564 bp

>AT80336 NZ_CP023019:c3277016-3276453 [Shewanella sp. WE21]
ATGATTATGTTTTCTGAGATTAAAGTTGCTCAAATGTCTGCGTTTATTCTGCACTTGAATGGGCAGAAAATGTCTTATCT
GAAGCTTATCAAAATATTATACTTAGCTGAGCGTGAAGCAGTGAGTCGTTGGGGTGACTCTATGAGTGGTGACAATTTTG
TGTCAATGCCTCACGGTCCTGTTTTATCACTAACATACAATCTGATCACTGGCGGTTCCAGAATGGAAAGTGACGGATGG
AACAAGTTTATTAGTGGATGTGCTAACTATGAAGTTTCGTCAAATCTAACCAATCCAGATAGAGATGATTGGGACGAACT
AAGTGATGCAGAACTGGCAATTATTGAATCAATTTTCAATAAGTTTAAACATCTTACCCGCTGGGAACTGGTTGACTACA
CTCATGATAATTGCAAAGAATGGATAGATCCTAAAGGCTCTTCAGCACCAATATCACTTGAAAAAATTATCTACGCGACA
TGTGATAAAAGTAAGACTGCAGCCTTAATTAGCTTTAGCAAATCAATGAATGAGCTTAGCGACGCGAGAAGCATTATACA
GTGA