Detailed information of TA system TA080335

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /DUF1778(antitoxin)
• Location: 2707171..2707967
• Replicon: chromosome
• Accession: NZ_CP023019
• Organism: Shewanella sp. WE21

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: CKQ84_RS11790
• Protein ID: WP_105251422.1
• Coordinates: 2707437..2707967 (+)
• Length: 177 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: CKQ84_RS11785
• Protein ID: WP_105251421.1
• Coordinates: 2707171..2707440 (+)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CKQ84_RS11765	2703358..2703822	-	465	WP_105251417.1	chemotaxis protein CheX	-
CKQ84_RS11770	2704781..2705266	+	486	WP_105251418.1	hypothetical protein	-
CKQ84_RS11775	2705375..2706070	+	696	WP_173913175.1	hypothetical protein	-
CKQ84_RS11780	2706648..2706998	+	351	WP_105251420.1	hypothetical protein	-
CKQ84_RS11785	2707171..2707440	+	270	WP_105251421.1	DUF1778 domain-containing protein	Antitoxin
CKQ84_RS11790	2707437..2707967	+	531	WP_105251422.1	GNAT family N-acetyltransferase	Toxin
CKQ84_RS11795	2708360..2708911	+	552	WP_105251423.1	tetratricopeptide repeat protein	-
CKQ84_RS11800	2709401..2709706	+	306	WP_105251424.1	hypothetical protein	-
CKQ84_RS11805	2709774..2710094	-	321	WP_105251425.1	hypothetical protein	-
CKQ84_RS11810	2710091..2710321	-	231	WP_105251426.1	hypothetical protein	-
CKQ84_RS11815	2710318..2710596	-	279	WP_105251427.1	hypothetical protein	-
CKQ84_RS11820	2710597..2710890	-	294	WP_105251428.1	hypothetical protein	-
CKQ84_RS11825	2710887..2711528	-	642	WP_105251429.1	hypothetical protein	-
CKQ84_RS11830	2711559..2711906	-	348	WP_011847795.1	hypothetical protein	-
CKQ84_RS11835	2711932..2712192	-	261	WP_006082040.1	pyocin activator PrtN family protein	-
CKQ84_RS11840	2712189..2712542	-	354	WP_105251430.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integron	-	-	2705375..2709706	4331

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (96-155)

Antitoxin

• Vibrio phage ICP1, Orf50 (5-81)

Sequences

Toxin

Protein

• Length: 177 a.a.
• Molecular weight: 19727.98 Da
• Isoelectric Point: 8.6014

>T80335 WP_105251422.1 NZ_CP023019:2707437-2707967 [Shewanella sp. WE21]
VSYSKTFKELDKSQHDRASFDCGEVELNDFIQTQAAKHMQAGISRTMVLPAATPLPNQKYPICSFYTIAPSSICRDTLPQ
AMGKKLPRYPIPVFLLAQLAVHKEFHGSGLGKASLIKALEYLWEINAHMRAYAIVVDCLTGQAESFYAKYGFEVLCEING
RVRMFIPMKTVGQLFT

Nucleotide

• Length: 531 bp

>T80335 NZ_CP023019:2707437-2707967 [Shewanella sp. WE21]
GTGAGTTACTCCAAGACTTTTAAAGAATTGGATAAATCACAACACGATAGAGCATCATTTGACTGTGGCGAAGTAGAGTT
AAACGATTTTATCCAAACTCAAGCAGCGAAACACATGCAAGCAGGTATTAGCCGTACAATGGTTTTACCTGCTGCTACGC
CATTACCCAATCAAAAATATCCAATTTGTTCATTTTATACTATCGCCCCAAGTTCAATTTGCCGTGATACCTTGCCACAA
GCCATGGGCAAAAAGTTACCACGCTATCCCATTCCGGTCTTTCTGCTTGCTCAACTTGCTGTCCATAAAGAGTTTCATGG
TAGTGGGTTAGGTAAAGCTAGCTTAATCAAAGCGCTAGAATATCTGTGGGAAATTAACGCTCACATGCGAGCTTATGCCA
TTGTTGTCGATTGTTTAACTGGCCAAGCTGAATCATTCTACGCCAAGTATGGTTTCGAGGTTCTTTGTGAAATCAACGGT
CGTGTAAGAATGTTTATTCCAATGAAAACAGTCGGTCAGTTATTCACTTAG

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 9933.40 Da
• Isoelectric Point: 4.9059

>AT80335 WP_105251421.1 NZ_CP023019:2707171-2707440 [Shewanella sp. WE21]
MATTRLDIRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDSTQVIAEHESITVKADVFDQFIMACDEAKAPNKALREAA
AFTKRGEFK

Nucleotide

• Length: 270 bp

>AT80335 NZ_CP023019:2707171-2707440 [Shewanella sp. WE21]
ATGGCAACTACAAGACTTGATATCCGTTTGGATGAAGAGATCAAAGCTAAGGCTGAGAAAGCATCGGCTTTGCTTGGTTT
AAAAAGCTTAACTGAATACGTTGTTCGCTTAATGGACGAAGATTCAACTCAGGTGATTGCTGAGCACGAAAGCATTACTG
TTAAAGCTGATGTATTCGACCAATTCATAATGGCTTGTGATGAGGCTAAGGCCCCGAACAAAGCATTGCGTGAAGCGGCA
GCATTTACTAAACGTGGTGAGTTTAAGTGA