Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) ygfYX/Cpta(toxin)
Location 397800..398469 Replicon chromosome
Accession NZ_CP023019
Organism Shewanella sp. WE21

Toxin (Protein)


Gene name ygfX Uniprot ID -
Locus tag CKQ84_RS01610 Protein ID WP_105249859.1
Coordinates 397800..398240 (-) Length 147 a.a.

Antitoxin (Protein)


Gene name ygfY Uniprot ID -
Locus tag CKQ84_RS01615 Protein ID WP_028760829.1
Coordinates 398221..398469 (-) Length 83 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKQ84_RS01585 393292..393765 - 474 WP_105249858.1 SoxR reducing system RseC family protein -
CKQ84_RS01590 393776..394708 - 933 WP_028760824.1 MucB/RseB C-terminal domain-containing protein -
CKQ84_RS01595 394721..395347 - 627 WP_028760825.1 anti-sigma factor -
CKQ84_RS01600 395389..395967 - 579 WP_028760826.1 RNA polymerase sigma factor RpoE -
CKQ84_RS01605 396158..397771 + 1614 WP_028760827.1 L-aspartate oxidase -
CKQ84_RS01610 397800..398240 - 441 WP_105249859.1 hypothetical protein Toxin
CKQ84_RS01615 398221..398469 - 249 WP_028760829.1 succinate dehydrogenase assembly factor 2 Antitoxin
CKQ84_RS01620 398555..399463 - 909 WP_028760830.1 transcriptional activator NhaR -
CKQ84_RS01625 399578..399964 - 387 WP_105249860.1 hypothetical protein -
CKQ84_RS01630 399967..401136 - 1170 WP_028760832.1 Na+/H+ antiporter NhaA -
CKQ84_RS01635 401254..402048 - 795 WP_105249861.1 thymidylate synthase -
CKQ84_RS01640 402045..402854 - 810 WP_105249862.1 prolipoprotein diacylglyceryl transferase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(6-135)

Antitoxin

(7-77)


Sequences


Toxin        


Download         Length: 147 a.a.        Molecular weight: 17188.19 Da        Isoelectric Point: 8.3018

>T80332 WP_105249859.1 NZ_CP023019:c398240-397800 [Shewanella sp. WE21]
VEDRHHSFSVKASFDQRLSLVVFIGVCSSSFLLWPQSDIIALSLLKYLFIVLVSIFLLSQLWRLQHWRLDFVLSDKGEGR
LSTGEHFQVLKRTWVTPFVCLIYIEVDTQLRLLLVWADMLNDTDYRHLCRLLLRAKMQQTKPHSEI

Download         Length: 441 bp

>T80332 NZ_CP023019:c398240-397800 [Shewanella sp. WE21]
GTGGAAGACCGGCACCATAGTTTCAGCGTAAAAGCCTCTTTCGACCAACGACTCTCGTTGGTCGTTTTTATTGGTGTCTG
TTCTAGCTCATTTCTGCTTTGGCCCCAAAGCGACATTATCGCCTTATCTCTGCTTAAATATTTGTTTATCGTACTTGTTA
GTATTTTTTTGCTGTCGCAGTTGTGGCGACTGCAGCATTGGCGTTTAGATTTTGTGCTGAGTGATAAAGGCGAGGGACGT
TTGTCAACGGGGGAGCACTTTCAGGTACTAAAACGCACTTGGGTCACGCCCTTTGTTTGCTTGATTTATATCGAAGTGGA
TACTCAGCTGCGGCTCTTGCTGGTTTGGGCTGATATGTTAAATGATACTGACTATCGACATTTATGTCGGCTGTTGCTGC
GGGCTAAAATGCAACAGACTAAACCTCATTCTGAGATTTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9733.39 Da        Isoelectric Point: 4.4929

>AT80332 WP_028760829.1 NZ_CP023019:c398469-398221 [Shewanella sp. WE21]
MELMNIARVRWACRRGMLELDVLLQPFVENFYQEMSDEDKTVFIRLLECEDPELFAWFMGHEVCPDTELARMIVKVRGRP
AP

Download         Length: 249 bp

>AT80332 NZ_CP023019:c398469-398221 [Shewanella sp. WE21]
TTGGAATTAATGAACATCGCAAGGGTTCGCTGGGCATGTCGTCGTGGGATGCTGGAATTAGACGTCTTGCTTCAACCTTT
TGTTGAAAACTTCTATCAAGAAATGTCCGATGAAGATAAAACCGTGTTTATCCGTTTGTTGGAATGTGAAGATCCAGAAT
TGTTTGCTTGGTTTATGGGCCATGAAGTGTGCCCTGACACTGAACTGGCTCGTATGATAGTAAAAGTCCGTGGAAGACCG
GCACCATAG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References