Detailed information of TA system TA080332

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ygfYX/Cpta(toxin)
• Location: 397800..398469
• Replicon: chromosome
• Accession: NZ_CP023019
• Organism: Shewanella sp. WE21

Toxin (Protein)

• Gene name: ygfX
• Uniprot ID: -
• Locus tag: CKQ84_RS01610
• Protein ID: WP_105249859.1
• Coordinates: 397800..398240 (-)
• Length: 147 a.a.

Antitoxin (Protein)

• Gene name: ygfY
• Uniprot ID: -
• Locus tag: CKQ84_RS01615
• Protein ID: WP_028760829.1
• Coordinates: 398221..398469 (-)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CKQ84_RS01585	393292..393765	-	474	WP_105249858.1	SoxR reducing system RseC family protein	-
CKQ84_RS01590	393776..394708	-	933	WP_028760824.1	MucB/RseB C-terminal domain-containing protein	-
CKQ84_RS01595	394721..395347	-	627	WP_028760825.1	anti-sigma factor	-
CKQ84_RS01600	395389..395967	-	579	WP_028760826.1	RNA polymerase sigma factor RpoE	-
CKQ84_RS01605	396158..397771	+	1614	WP_028760827.1	L-aspartate oxidase	-
CKQ84_RS01610	397800..398240	-	441	WP_105249859.1	hypothetical protein	Toxin
CKQ84_RS01615	398221..398469	-	249	WP_028760829.1	succinate dehydrogenase assembly factor 2	Antitoxin
CKQ84_RS01620	398555..399463	-	909	WP_028760830.1	transcriptional activator NhaR	-
CKQ84_RS01625	399578..399964	-	387	WP_105249860.1	hypothetical protein	-
CKQ84_RS01630	399967..401136	-	1170	WP_028760832.1	Na+/H+ antiporter NhaA	-
CKQ84_RS01635	401254..402048	-	795	WP_105249861.1	thymidylate synthase	-
CKQ84_RS01640	402045..402854	-	810	WP_105249862.1	prolipoprotein diacylglyceryl transferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (6-135)

Antitoxin

• Flavinator of succinate dehydrogenase (7-77)

Sequences

Toxin

Protein

• Length: 147 a.a.
• Molecular weight: 17188.19 Da
• Isoelectric Point: 8.3018

>T80332 WP_105249859.1 NZ_CP023019:c398240-397800 [Shewanella sp. WE21]
VEDRHHSFSVKASFDQRLSLVVFIGVCSSSFLLWPQSDIIALSLLKYLFIVLVSIFLLSQLWRLQHWRLDFVLSDKGEGR
LSTGEHFQVLKRTWVTPFVCLIYIEVDTQLRLLLVWADMLNDTDYRHLCRLLLRAKMQQTKPHSEI

Nucleotide

• Length: 441 bp

>T80332 NZ_CP023019:c398240-397800 [Shewanella sp. WE21]
GTGGAAGACCGGCACCATAGTTTCAGCGTAAAAGCCTCTTTCGACCAACGACTCTCGTTGGTCGTTTTTATTGGTGTCTG
TTCTAGCTCATTTCTGCTTTGGCCCCAAAGCGACATTATCGCCTTATCTCTGCTTAAATATTTGTTTATCGTACTTGTTA
GTATTTTTTTGCTGTCGCAGTTGTGGCGACTGCAGCATTGGCGTTTAGATTTTGTGCTGAGTGATAAAGGCGAGGGACGT
TTGTCAACGGGGGAGCACTTTCAGGTACTAAAACGCACTTGGGTCACGCCCTTTGTTTGCTTGATTTATATCGAAGTGGA
TACTCAGCTGCGGCTCTTGCTGGTTTGGGCTGATATGTTAAATGATACTGACTATCGACATTTATGTCGGCTGTTGCTGC
GGGCTAAAATGCAACAGACTAAACCTCATTCTGAGATTTAG

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9733.39 Da
• Isoelectric Point: 4.4929

>AT80332 WP_028760829.1 NZ_CP023019:c398469-398221 [Shewanella sp. WE21]
MELMNIARVRWACRRGMLELDVLLQPFVENFYQEMSDEDKTVFIRLLECEDPELFAWFMGHEVCPDTELARMIVKVRGRP
AP

Nucleotide

• Length: 249 bp

>AT80332 NZ_CP023019:c398469-398221 [Shewanella sp. WE21]
TTGGAATTAATGAACATCGCAAGGGTTCGCTGGGCATGTCGTCGTGGGATGCTGGAATTAGACGTCTTGCTTCAACCTTT
TGTTGAAAACTTCTATCAAGAAATGTCCGATGAAGATAAAACCGTGTTTATCCGTTTGTTGGAATGTGAAGATCCAGAAT
TGTTTGCTTGGTTTATGGGCCATGAAGTGTGCCCTGACACTGAACTGGCTCGTATGATAGTAAAAGTCCGTGGAAGACCG
GCACCATAG