Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1744860..1745523 Replicon chromosome
Accession NZ_CP023009
Organism Lonsdalea britannica strain 477

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag CKQ53_RS08240 Protein ID WP_094118278.1
Coordinates 1745107..1745523 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag CKQ53_RS08235 Protein ID WP_094118277.1
Coordinates 1744860..1745126 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKQ53_RS08210 1739887..1740516 + 630 WP_118894859.1 hypothetical protein -
CKQ53_RS08215 1740513..1741838 + 1326 WP_118894861.1 MHS family MFS transporter -
CKQ53_RS08220 1741891..1742493 - 603 WP_094118275.1 HD domain-containing protein -
CKQ53_RS08225 1742715..1743362 + 648 WP_118894863.1 hemolysin III family protein -
CKQ53_RS08230 1743647..1744627 - 981 WP_118894865.1 tRNA-modifying protein YgfZ -
CKQ53_RS08235 1744860..1745126 + 267 WP_094118277.1 FAD assembly factor SdhE Antitoxin
CKQ53_RS08240 1745107..1745523 + 417 WP_094118278.1 protein YgfX Toxin
CKQ53_RS08245 1745802..1746755 + 954 WP_094118279.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
CKQ53_RS08250 1746812..1747345 - 534 WP_094118280.1 flavodoxin FldB -
CKQ53_RS08255 1747503..1748831 - 1329 WP_085652689.1 MHS family MFS transporter -
CKQ53_RS08260 1749084..1749983 + 900 WP_085652688.1 site-specific tyrosine recombinase XerD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16176.17 Da        Isoelectric Point: 11.9252

>T80328 WP_094118278.1 NZ_CP023009:1745107-1745523 [Lonsdalea britannica]
VAQWQCDLKVSWRMQLFSLLVHGIMVLLILLAPWPSGYAPLWLGLVSLVMFGFIRSQRNIKSRHGAISLHGERHLRWQQR
EWRIVKRPWMLKSGILLSLRAADGAALEQRLWLSSDSMGRDEWRHLRQLLLRKDRCAG

Download         Length: 417 bp

>T80328 NZ_CP023009:1745107-1745523 [Lonsdalea britannica]
GTGGCCCAGTGGCAATGTGATCTTAAAGTTTCCTGGCGCATGCAGCTGTTCTCTCTGCTGGTGCACGGGATTATGGTGCT
CTTGATTCTGCTGGCCCCGTGGCCGAGTGGTTATGCGCCGCTATGGCTGGGGCTGGTGTCTCTGGTGATGTTCGGATTCA
TTCGTAGCCAGCGCAATATCAAATCTCGCCACGGCGCGATCTCGCTGCACGGTGAACGTCATCTGCGCTGGCAGCAGCGA
GAGTGGCGCATCGTCAAACGGCCGTGGATGCTGAAGAGCGGTATTCTGCTGTCGCTGCGGGCAGCGGACGGCGCAGCTCT
GGAACAGCGACTATGGCTCTCCTCGGACAGTATGGGGCGGGATGAGTGGCGGCATCTGCGTCAGCTTTTGCTGCGGAAGG
ACCGCTGCGCAGGGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10388.88 Da        Isoelectric Point: 6.0666

>AT80328 WP_094118277.1 NZ_CP023009:1744860-1745126 [Lonsdalea britannica]
MDINDKARIHWACRRGMRELDISIMPFFEHDYDALNDSDKSAFVRLLQCDDPDLFNWLMNHGEPSDLELKRMVSLIQTRN
KHRGPVAM

Download         Length: 267 bp

>AT80328 NZ_CP023009:1744860-1745126 [Lonsdalea britannica]
ATGGATATCAATGATAAAGCACGCATTCACTGGGCCTGTCGGCGCGGCATGCGTGAGCTGGATATTTCCATCATGCCGTT
TTTCGAGCATGACTACGATGCATTGAACGATAGCGACAAAAGCGCCTTTGTCCGCCTGCTGCAGTGCGACGATCCCGATC
TGTTCAACTGGCTGATGAATCACGGCGAGCCATCAGATCTGGAGCTTAAACGCATGGTTTCCCTTATTCAGACGCGAAAT
AAACACCGTGGCCCAGTGGCAATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References