Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 272384..272967 Replicon chromosome
Accession NZ_CP023005
Organism Bifidobacterium adolescentis strain 6

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CKK50_RS01070 Protein ID WP_003807675.1
Coordinates 272384..272683 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CKK50_RS01075 Protein ID WP_117319828.1
Coordinates 272683..272967 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKK50_RS01060 269067..269795 + 729 WP_003807670.1 type 1 glutamine amidotransferase -
CKK50_RS01065 270107..272287 + 2181 WP_117319827.1 ABC-F family ATP-binding cassette domain-containing protein -
CKK50_RS01070 272384..272683 - 300 WP_003807675.1 type II toxin-antitoxin system YafQ family toxin Toxin
CKK50_RS01075 272683..272967 - 285 WP_117319828.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
CKK50_RS01080 273070..273906 - 837 WP_117319829.1 hypothetical protein -
CKK50_RS01085 274090..274629 + 540 WP_003807679.1 hypothetical protein -
CKK50_RS09225 274622..275140 + 519 WP_130082043.1 hypothetical protein -
CKK50_RS01090 275199..276353 - 1155 WP_046998989.1 ATP-binding protein -
CKK50_RS01095 276356..276985 - 630 WP_117319830.1 response regulator transcription factor -
CKK50_RS01100 277122..277763 + 642 WP_039774713.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-98)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-72)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11662.09 Da        Isoelectric Point: 8.0955

>T80325 WP_003807675.1 NZ_CP023005:c272683-272384 [Bifidobacterium adolescentis]
MGRLTADFAKAFSRDLKKNAKRRNWNLTELEKVIDLVVENTPETLEELRRRHNMHTLSGNWRGRYECHVANAGDWLVIWS
SNDSVAFFERTGSHDELFR

Download         Length: 300 bp

>T80325 NZ_CP023005:c272683-272384 [Bifidobacterium adolescentis]
ATGGGCCGGTTGACCGCCGACTTCGCGAAGGCCTTCAGCCGCGATCTGAAAAAGAACGCCAAACGGCGTAACTGGAACCT
GACCGAGCTTGAAAAAGTCATCGATCTGGTAGTGGAGAACACCCCGGAAACGCTGGAGGAGCTGCGCCGCCGCCACAACA
TGCACACCCTGTCCGGCAATTGGCGCGGGCGATACGAATGCCATGTCGCCAATGCCGGGGACTGGCTAGTGATCTGGTCA
TCGAACGATTCAGTCGCATTCTTCGAACGCACCGGCAGCCACGACGAATTATTCCGGTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10261.68 Da        Isoelectric Point: 5.8150

>AT80325 WP_117319828.1 NZ_CP023005:c272967-272683 [Bifidobacterium adolescentis]
MRFLMSASTLTIRMDDKLKRSAADVAEYYGLDLSSVVRAVFKQMVNTGRIPLTFAPEEPNGESLNAAAEADSFMASGKTG
RFTNGHDLLEAAMR

Download         Length: 285 bp

>AT80325 NZ_CP023005:c272967-272683 [Bifidobacterium adolescentis]
ATGAGGTTTCTGATGAGTGCATCAACGTTGACCATACGGATGGATGACAAACTCAAGCGTTCGGCCGCCGACGTGGCCGA
ATATTATGGCTTGGATCTCTCGTCAGTGGTGCGCGCCGTATTCAAGCAAATGGTGAATACCGGGCGCATCCCATTGACGT
TCGCCCCCGAGGAGCCTAATGGCGAAAGCCTGAACGCCGCTGCCGAAGCGGACAGCTTCATGGCATCGGGCAAGACGGGG
CGTTTTACCAACGGACACGACCTGCTCGAAGCGGCGATGCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References