Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 1327946..1328640 Replicon plasmid p11515TR-B
Accession NZ_CP023000
Organism Rhizobium sp. 11515TR strain 10195

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CKA34_RS32790 Protein ID WP_095438740.1
Coordinates 1328200..1328640 (+) Length 147 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CKA34_RS32785 Protein ID WP_095438739.1
Coordinates 1327946..1328197 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKA34_RS32765 1323302..1324129 + 828 WP_095438735.1 helix-turn-helix domain-containing protein -
CKA34_RS32770 1324192..1325535 - 1344 WP_095438736.1 guanine deaminase -
CKA34_RS32775 1325532..1326770 - 1239 WP_095438737.1 urate hydroxylase PuuD -
CKA34_RS32780 1326926..1327864 + 939 WP_095438738.1 LysR family transcriptional regulator -
CKA34_RS32785 1327946..1328197 + 252 WP_095438739.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CKA34_RS32790 1328200..1328640 + 441 WP_095438740.1 type II toxin-antitoxin system VapC family toxin Toxin
CKA34_RS32795 1328630..1329481 - 852 WP_095438741.1 xanthine dehydrogenase accessory protein XdhC -
CKA34_RS32800 1329486..1331840 - 2355 WP_095438742.1 xanthine dehydrogenase molybdopterin binding subunit -
CKA34_RS32805 1331844..1333328 - 1485 WP_095438743.1 xanthine dehydrogenase small subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB 1..1497349 1497349


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-65)


Sequences

Toxin        


Download         Length: 147 a.a.        Molecular weight: 15989.48 Da        Isoelectric Point: 8.6171

>T80322 WP_095438740.1 NZ_CP023000:1328200-1328640 [Rhizobium sp. 11515TR]
MYLLDTNIVSADAPTKRQVGVEAFAAWLRANNDRLYLSAITIAEIEAGIARMVRIGATTKAEHLRRWLAAVEHFYAGRIL
PFGVEEARHAGLMLDRARAHDPGFEDIAIAATAAAHGFTVLTANVRHFEPLGVPLANPLKQLPVIR

Download         Length: 441 bp

>T80322 NZ_CP023000:1328200-1328640 [Rhizobium sp. 11515TR]
TTGTATCTTCTGGATACCAATATCGTATCGGCCGATGCGCCGACCAAACGCCAAGTCGGCGTTGAGGCATTCGCGGCCTG
GCTGCGCGCGAATAATGACCGGCTTTATCTTTCGGCGATCACCATCGCCGAGATCGAGGCAGGCATCGCCCGCATGGTTA
GGATTGGGGCGACGACGAAGGCGGAGCACTTGCGCCGCTGGCTCGCTGCGGTGGAACATTTCTATGCCGGCCGTATCCTG
CCCTTCGGAGTTGAGGAGGCGCGGCATGCTGGCCTGATGCTTGACCGGGCGCGTGCTCACGACCCCGGCTTCGAGGACAT
TGCCATCGCTGCGACTGCTGCCGCTCATGGTTTCACCGTTTTGACGGCCAATGTGCGACATTTTGAACCGCTTGGCGTGC
CTCTCGCCAATCCCTTAAAGCAGTTGCCTGTTATCCGATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9171.50 Da        Isoelectric Point: 8.8077

>AT80322 WP_095438739.1 NZ_CP023000:1327946-1328197 [Rhizobium sp. 11515TR]
MKEIQLKDAKATLSAVVDQAVAGEPTVITRHGRKEAVLVSFEEWQRVSRVPDFADLLLAFPGEPADIPERSRKPARSLRG
NGF

Download         Length: 252 bp

>AT80322 NZ_CP023000:1327946-1328197 [Rhizobium sp. 11515TR]
ATGAAGGAAATCCAGCTCAAGGATGCGAAGGCGACGCTTTCGGCCGTGGTCGATCAAGCGGTGGCCGGCGAGCCGACCGT
TATTACCCGCCATGGCCGGAAGGAAGCGGTGCTGGTTTCCTTCGAGGAATGGCAACGCGTCTCCAGGGTACCTGATTTCG
CCGATCTGCTTCTCGCCTTTCCCGGCGAGCCCGCCGATATTCCGGAGCGATCGCGAAAACCCGCACGTTCATTGCGTGGA
AACGGCTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References