Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1068359..1069002 Replicon chromosome
Accession NZ_CP022998
Organism Rhizobium sp. 11515TR strain 10195

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CKA34_RS05225 Protein ID WP_095433768.1
Coordinates 1068359..1068763 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CKA34_RS05230 Protein ID WP_095433769.1
Coordinates 1068760..1069002 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKA34_RS05190 1063491..1064396 + 906 WP_095433761.1 LysR family transcriptional regulator -
CKA34_RS05195 1064397..1065272 - 876 WP_095433762.1 LysR family transcriptional regulator -
CKA34_RS05200 1065371..1066654 + 1284 WP_095433763.1 MFS transporter -
CKA34_RS05205 1066670..1067056 + 387 WP_095433764.1 VOC family protein -
CKA34_RS05210 1067148..1067489 + 342 WP_095433765.1 metalloregulator ArsR/SmtB family transcription factor -
CKA34_RS05215 1067473..1067958 + 486 WP_095433766.1 SRPBCC domain-containing protein -
CKA34_RS05220 1067958..1068362 + 405 WP_095433767.1 GFA family protein -
CKA34_RS05225 1068359..1068763 - 405 WP_095433768.1 type II toxin-antitoxin system VapC family toxin Toxin
CKA34_RS05230 1068760..1069002 - 243 WP_095433769.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
CKA34_RS05235 1069068..1069742 - 675 WP_095433770.1 hypothetical protein -
CKA34_RS05240 1069812..1071473 - 1662 WP_095433771.1 urocanate hydratase -
CKA34_RS05245 1071729..1072058 - 330 WP_037149213.1 TfoX/Sxy family protein -
CKA34_RS05250 1072077..1073177 - 1101 WP_095433772.1 DUF917 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-120)

Antitoxin

SpoVT-AbrB domain

(7-43)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14962.20 Da        Isoelectric Point: 6.4876

>T80315 WP_095433768.1 NZ_CP022998:c1068763-1068359 [Rhizobium sp. 11515TR]
VKFLLDSNAVIALMKGHPGFVSELRRHKPQDFAIPAIVAHELFYGAYKGQRVSENLARVDALQFETLDFDKQDARVAGEI
RAALAFLGTPIGAYDVLIAGQAVARDLILITHNVREFERVLKLRFEDWESLPSG

Download         Length: 405 bp

>T80315 NZ_CP022998:c1068763-1068359 [Rhizobium sp. 11515TR]
GTGAAGTTTCTGCTCGACAGCAATGCCGTCATCGCTCTGATGAAAGGACACCCCGGCTTTGTCAGCGAGCTTCGCAGACA
TAAGCCCCAGGATTTCGCCATTCCGGCCATCGTCGCACACGAGCTGTTTTATGGTGCCTATAAAGGGCAGCGCGTTTCCG
AAAATCTGGCACGTGTCGATGCCTTGCAATTCGAGACGCTGGATTTCGACAAGCAAGATGCCCGTGTAGCTGGCGAAATT
CGCGCGGCCCTTGCTTTTCTTGGCACGCCGATCGGCGCTTATGACGTTCTGATCGCGGGACAAGCGGTCGCCCGCGATCT
GATCCTGATAACGCACAATGTCAGGGAGTTTGAACGCGTTCTCAAGCTACGTTTCGAAGACTGGGAATCCTTGCCGAGTG
GCTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9297.43 Da        Isoelectric Point: 4.1860

>AT80315 WP_095433769.1 NZ_CP022998:c1069002-1068760 [Rhizobium sp. 11515TR]
MDTAKIFWSGRSQAVRLPKEFRIDGEEVRIRRQGKAIILEPIAEDWDWLEAITGPIDQDFAEAAEEEPAEQQRPELDIFK

Download         Length: 243 bp

>AT80315 NZ_CP022998:c1069002-1068760 [Rhizobium sp. 11515TR]
ATGGACACCGCAAAGATCTTCTGGTCCGGCCGCTCACAGGCCGTCCGTTTGCCAAAGGAATTCCGTATCGACGGCGAGGA
AGTGCGCATCCGCCGGCAAGGAAAAGCAATCATTCTGGAGCCGATCGCCGAAGATTGGGATTGGCTGGAAGCGATCACCG
GGCCAATCGACCAAGACTTCGCAGAAGCAGCCGAAGAAGAGCCGGCTGAACAGCAACGCCCCGAGCTGGATATCTTCAAG
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References