Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 263061..263206 Replicon chromosome
Accession NZ_CP022997
Organism Klebsiella pneumoniae strain 721005

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 263097..263199 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 263061..263206 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CI946_RS01195 258191..260251 + 2061 WP_004151449.1 oligopeptidase B -
CI946_RS01200 260255..260914 - 660 WP_002911407.1 exodeoxyribonuclease X -
CI946_RS01205 260993..261223 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CI946_RS01210 261336..261710 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CI946_RS01215 261714..262583 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
CI946_RS01220 262600..262938 + 339 WP_002911404.1 YebY family protein -
- 263061..263206 - 146 - - Antitoxin
- 263097..263199 + 103 - - Toxin
CI946_RS27750 263574..263717 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CI946_RS01230 263822..264790 - 969 WP_004151446.1 VirK/YbjX family protein -
CI946_RS01235 264947..265600 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
CI946_RS01240 265597..265788 - 192 WP_002911395.1 YebW family protein -
CI946_RS01245 265886..266125 - 240 WP_002911393.1 YebV family protein -
CI946_RS01250 266241..267674 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T80297 NZ_CP022997:263097-263199 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT80297 NZ_CP022997:c263206-263061 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References