Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 2533138..2533653 Replicon chromosome
Accession NZ_CP022987
Organism Pusillimonas thiosulfatoxidans strain YE3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CKA81_RS12290 Protein ID WP_128355519.1
Coordinates 2533378..2533653 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CKA81_RS12285 Protein ID WP_128355518.1
Coordinates 2533138..2533332 (+) Length 65 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKA81_RS12265 2529136..2529381 - 246 WP_128355514.1 DUF1289 domain-containing protein -
CKA81_RS12270 2529384..2530547 - 1164 WP_164878391.1 methionine adenosyltransferase -
CKA81_RS12275 2530793..2531647 + 855 WP_128355516.1 lysophospholipid acyltransferase family protein -
CKA81_RS12280 2531644..2532534 + 891 WP_128355517.1 lysophospholipid acyltransferase family protein -
CKA81_RS12285 2533138..2533332 + 195 WP_128355518.1 antitoxin Antitoxin
CKA81_RS12290 2533378..2533653 + 276 WP_128355519.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CKA81_RS12295 2534071..2534964 + 894 WP_128355520.1 diaminopimelate epimerase -
CKA81_RS12300 2534961..2535647 + 687 WP_128355521.1 DUF484 family protein -
CKA81_RS12305 2535657..2536607 + 951 WP_128355522.1 tyrosine recombinase XerC -
CKA81_RS12310 2536608..2537618 - 1011 WP_128356784.1 zinc ABC transporter substrate-binding protein -
CKA81_RS12315 2537633..2538531 - 899 Protein_2406 metal ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10451.11 Da        Isoelectric Point: 9.7418

>T80291 WP_128355519.1 NZ_CP022987:2533378-2533653 [Pusillimonas thiosulfatoxidans]
VLKISWRSTAFDDLAEIITYIADRNLQAARDLKSRIQASILQIAVYPYLGRPGRLSGTREIVVHPNYIVIYRITPTDIEV
ISVLHARREYP

Download         Length: 276 bp

>T80291 NZ_CP022987:2533378-2533653 [Pusillimonas thiosulfatoxidans]
GTGCTTAAAATCTCCTGGCGTTCTACCGCCTTCGATGACTTGGCCGAGATCATCACCTACATTGCCGACCGCAACCTGCA
AGCAGCAAGAGATCTCAAAAGCCGTATACAAGCCTCCATACTACAAATAGCCGTGTATCCATACCTAGGCCGACCCGGAC
GCCTCTCAGGCACCCGCGAGATCGTGGTGCACCCCAACTACATAGTCATTTACAGAATCACGCCTACCGATATCGAGGTC
ATCAGCGTCCTACACGCCAGACGGGAATACCCCTAA

Antitoxin


Download         Length: 65 a.a.        Molecular weight: 7194.10 Da        Isoelectric Point: 5.5428

>AT80291 WP_128355518.1 NZ_CP022987:2533138-2533332 [Pusillimonas thiosulfatoxidans]
MSIALSPIVSEFNTEEQAASHDRWLRAKVQASLADPRPSIPHDQVMARMDAIIEKAQKETPNHE

Download         Length: 195 bp

>AT80291 NZ_CP022987:2533138-2533332 [Pusillimonas thiosulfatoxidans]
ATGAGCATTGCCCTCTCTCCGATCGTTTCGGAATTCAACACCGAAGAACAAGCGGCCAGCCACGATCGCTGGCTGCGCGC
GAAGGTCCAAGCCAGCCTGGCCGATCCACGTCCCAGCATTCCACATGACCAGGTCATGGCGCGTATGGACGCCATTATTG
AGAAGGCGCAGAAAGAGACGCCAAACCACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References