Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-VagC
Location 2098558..2099228 Replicon chromosome
Accession NZ_CP022987
Organism Pusillimonas thiosulfatoxidans strain YE3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CKA81_RS10070 Protein ID WP_128355141.1
Coordinates 2098558..2098959 (-) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CKA81_RS10075 Protein ID WP_128355142.1
Coordinates 2098956..2099228 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKA81_RS10045 2093953..2094498 - 546 WP_128355136.1 peroxiredoxin -
CKA81_RS10050 2094510..2094752 - 243 WP_128355137.1 DUF3820 family protein -
CKA81_RS10055 2094797..2096956 - 2160 WP_128355138.1 TonB-dependent siderophore receptor -
CKA81_RS10060 2097216..2098346 + 1131 WP_128355139.1 PepSY domain-containing protein -
CKA81_RS10065 2098343..2098546 + 204 WP_128355140.1 hypothetical protein -
CKA81_RS10070 2098558..2098959 - 402 WP_128355141.1 type II toxin-antitoxin system VapC family toxin Toxin
CKA81_RS10075 2098956..2099228 - 273 WP_128355142.1 antitoxin Antitoxin
CKA81_RS10080 2099301..2099828 - 528 WP_128355143.1 hypothetical protein -
CKA81_RS10085 2099734..2101089 - 1356 WP_128356739.1 polysaccharide lyase family 1 protein -
CKA81_RS10090 2101117..2103036 - 1920 WP_128355144.1 Vi polysaccharide transport protein VexE -
CKA81_RS10095 2103029..2104060 - 1032 WP_128356742.1 sugar ABC transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(16-54)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14253.51 Da        Isoelectric Point: 6.9668

>T80289 WP_128355141.1 NZ_CP022987:c2098959-2098558 [Pusillimonas thiosulfatoxidans]
VNGYLLDTNILSDLLRNPDGLAAHQIQRVGHHAVCTSIVVAAEMRYGCAKKGSPKLLAKVRSLLDTLPVLPLDLPVDAAY
GSIRTELEAAGQPIGANDLLIAAHAHTLGLTLVTGNTREFDRIRGLVVENWLV

Download         Length: 402 bp

>T80289 NZ_CP022987:c2098959-2098558 [Pusillimonas thiosulfatoxidans]
GTGAACGGCTATTTGCTGGACACCAATATCCTCAGTGATCTGTTGCGCAATCCTGACGGCCTGGCGGCCCACCAAATACA
GCGAGTCGGTCACCATGCGGTCTGTACCAGTATCGTCGTTGCCGCTGAGATGCGCTACGGGTGCGCCAAAAAGGGGTCCC
CCAAGTTGCTGGCCAAGGTGCGGAGCTTGCTCGATACGCTGCCTGTGCTGCCTCTCGATCTACCGGTCGACGCGGCGTAC
GGGAGCATCCGGACTGAACTGGAAGCCGCAGGGCAGCCTATCGGCGCCAACGACCTGTTGATCGCTGCACACGCCCATAC
GCTAGGCCTAACACTTGTGACCGGCAACACCCGGGAGTTCGACCGTATTCGGGGGCTTGTCGTGGAAAATTGGTTGGTGT
GA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10130.49 Da        Isoelectric Point: 4.4002

>AT80289 WP_128355142.1 NZ_CP022987:c2099228-2098956 [Pusillimonas thiosulfatoxidans]
MTTPVPSSRSREAKLFRNNRSQAVRIPAEFELPGDRVLIHREGARLIIEPVSGPSNILELLAEWKNDEPLGPEDWFPEIS
DMPAAPEDIL

Download         Length: 273 bp

>AT80289 NZ_CP022987:c2099228-2098956 [Pusillimonas thiosulfatoxidans]
ATGACTACTCCCGTACCTTCTTCGAGATCTCGTGAGGCCAAGCTATTTCGAAATAACCGCAGCCAAGCTGTCCGCATTCC
AGCCGAATTTGAACTGCCCGGCGATCGGGTGCTGATCCATCGTGAAGGAGCGAGGCTTATTATCGAGCCCGTATCCGGGC
CAAGCAACATACTCGAGCTGCTGGCCGAATGGAAGAACGATGAGCCGCTCGGGCCAGAAGACTGGTTTCCTGAAATCTCA
GACATGCCTGCGGCGCCGGAGGATATTTTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References