Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 573027..573622 Replicon chromosome
Accession NZ_CP022987
Organism Pusillimonas thiosulfatoxidans strain YE3

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag CKA81_RS02770 Protein ID WP_128353937.1
Coordinates 573317..573622 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CKA81_RS02765 Protein ID WP_128353936.1
Coordinates 573027..573320 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKA81_RS02735 568411..569475 - 1065 WP_128353930.1 AI-2E family transporter -
CKA81_RS02740 569501..570721 - 1221 WP_128353931.1 AI-2E family transporter -
CKA81_RS02745 570835..571230 - 396 WP_128353932.1 VOC family protein -
CKA81_RS02750 571305..572192 + 888 WP_128353933.1 DNA/RNA non-specific endonuclease -
CKA81_RS02755 572260..572451 + 192 WP_128353934.1 hypothetical protein -
CKA81_RS02760 572459..572746 - 288 WP_128353935.1 hypothetical protein -
CKA81_RS02765 573027..573320 - 294 WP_128353936.1 putative addiction module antidote protein Antitoxin
CKA81_RS02770 573317..573622 - 306 WP_128353937.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CKA81_RS02780 574022..574567 - 546 WP_128353938.1 ferritin-like domain-containing protein -
CKA81_RS02785 574732..575619 + 888 WP_128356498.1 DMT family transporter -
CKA81_RS02790 575641..576834 - 1194 WP_128353939.1 patatin-like phospholipase family protein -
CKA81_RS02795 576831..577736 - 906 WP_128353940.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(5-94)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11603.41 Da        Isoelectric Point: 10.6535

>T80287 WP_128353937.1 NZ_CP022987:c573622-573317 [Pusillimonas thiosulfatoxidans]
MNSINRTAKFNEWLADLKDLKARAKVIIRMRQAAQGNFGDIKTISDGVSEMRIHFGPGYRIYYARDGRAVYLLLIGGNKS
TQKRDIKTAISMWKQIQEEQP

Download         Length: 306 bp

>T80287 NZ_CP022987:c573622-573317 [Pusillimonas thiosulfatoxidans]
ATGAATTCGATTAACCGAACCGCCAAATTTAATGAATGGCTAGCCGACCTCAAGGACTTGAAAGCAAGGGCGAAAGTAAT
TATTCGCATGCGGCAAGCAGCCCAAGGCAACTTCGGCGACATAAAGACCATCAGTGATGGTGTTTCCGAGATGCGTATTC
ACTTCGGCCCCGGCTATCGTATTTACTATGCCCGTGATGGCCGAGCCGTATACCTCTTGTTGATTGGCGGCAACAAGTCT
ACGCAGAAGCGGGACATCAAGACCGCCATATCCATGTGGAAACAGATACAAGAGGAACAGCCATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10266.81 Da        Isoelectric Point: 4.8359

>AT80287 WP_128353936.1 NZ_CP022987:c573320-573027 [Pusillimonas thiosulfatoxidans]
MTTIKIAPFDAAEYLDSEEAIAEYLSAALEEDDPALFLAALSDVAKARGMTKMAKDAGLGRESLYKALAPGAKPRYDTVL
KLARAAGVKLTVEPAHA

Download         Length: 294 bp

>AT80287 NZ_CP022987:c573320-573027 [Pusillimonas thiosulfatoxidans]
ATGACCACCATCAAAATAGCGCCCTTTGACGCAGCCGAATATCTTGACAGCGAAGAAGCAATTGCCGAGTACCTATCTGC
AGCGTTAGAGGAAGACGACCCCGCCCTCTTCCTTGCGGCGCTATCAGATGTTGCCAAAGCCAGGGGCATGACCAAAATGG
CCAAGGATGCGGGTCTTGGTCGCGAAAGCCTGTACAAGGCATTGGCTCCCGGAGCTAAGCCACGCTATGACACCGTGCTA
AAGCTAGCTCGTGCCGCTGGCGTGAAGCTCACAGTAGAGCCTGCTCACGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References